Skip to main content

Table 3 Complications in the course of the disease

From: Dramatic reduction of mortality in pneumococcal meningitis

  2003–2015 1984–2002 P value
Intracranial complicationsa 52.7 % 74.7 % 0.010
Brain edema 14.5 % 28.7 % 0.066
Epileptic seizures 14.5 % 27.6 % 0.098
Cerebral ischemia 12.7 % 18.4 % 0.485
Hydrocepahlus 10.9 %b 16.1 % 0.464
Sinus thrombosis 7.3 % 9.1 % 0.766
Intracranial bleeding 3.6 % 9.1 % 0.316
Cerebral vasculopthy 40 % not assessed  
Hearing loss 32.7 % 19.5 % 0.23
Systemic complications 34.5 % 48.3 % 0.12
Pneumonia 21.8 % 21.8 % 1.0
Sepsis 16.4 % 31.0 % 0.074
Renal failure 5.5 % 11.5 % 0.371
Disseminated intravasal coagulation 3.6 % 23 % 0.002
  1. aNot including cerebral vasculopathy, as this was not assessed in the previous study period. See main text for details. bFive of six patients required an external ventricular drain