Table 2 Characteristics of cases identified using explicit codes (n = 138 517)
From: Use of explicit ICD9-CM codes to identify adult severe sepsis: impacts on epidemiological estimates
|  | Code 785.52a n = 93 380 (67 %) | Code 995.92a n = 45 137 (33 %) | RR (95 % CI) |
|---|---|---|---|
Men | 54 906 (58.8) | 25 196 (55.8) | 1.05 (1.04, 1.07) |
Age group (years) | |||
 18–44 | 7434 (8.0) | 2921 (6.5) | 1.23 (1.18, 1.28) |
 45–64 | 22 135 (23.7) | 7994 (17.7) | 1.34 (1.30, 1.37) |
 65–74 | 21 025 (22.5) | 8350 (18.5) | 1.22 (1.19, 1.25) |
 75–84 | 29 374 (31.4) | 14 974 (33.2) | 0.95 (0.93, 0.97) |
  > 84 | 13 412 (14.4) | 10 898 (24.1) | 0.59 (0.58, 0.61) |
Charlson comorbidity index | |||
 0 | 23 482 (25.2) | 9361 (20.7) | 1.21 (1.18, 1.24) |
 1–2 | 43 180 (46.2) | 20 640 (45.7) | 1.01 (0.99, 1.03) |
 3–4 | 17 029 (18.2) | 9767 (21.6) | 0.84 (0.82, 0.86) |
  > 4 | 9689 (10.4) | 5369 (11.9) | 0.87 (0.84, 0.90) |
Detailed comorbiditiesb | |||
 Diabetes | 18 184 (19.5) | 11 059 (24.5) | 0.79 (0.78, 0.81) |
 Cancer | 19 671 (21.1) | 8393 (18.6) | 1.13 (1.10, 1.16) |
 Chronic heart failure | 13 892 (14.9) | 9161 (20.3) | 0.73 (0.71, 0.75) |
 COPD | 13 488 (14.4) | 7136 (15.8) | 0.91 (0.89, 0.94) |
 Chronic renal disease | 11 327 (12.1) | 6948 (15.4) | 0.79 (0.76, 0.81) |
 Liver disease | 11 922 (12.8) | 5486 (12.1) | 1.05 (1.02, 1.08) |
 Cerebrovascular disease | 6155 (6.6) | 4239 (9.4) | 0.70 (0.67, 0.73) |
 Dementia | 4237 (4.5) | 3902 (8.6) | 0.52 (0.50, 0.55) |
 Peripheral vascular disease | 4726 (5.1) | 2789 (6.2) | 0.82 (0.78, 0.86) |
 Acute myocardial infarction | 3690 (4.0) | 1897 (4.2) | 0.94 (0.89, 0.99) |
Surgical pathology | 30 850 (33.0) | 10 668 (23.6) | 1.40 (1.37, 1.43) |
Microbiological data | |||
 Identified pathogensb | 35 418 (37.9) | 17 528 (38.8) | 0.98 (0.96, 1.0) |
 Gram-positive pathogens | 14 318 (40.4) | 7273 (41.5) | 0.97 (0.95, 1.01) |
 Gram-negative pathogens | 24 639 (69.6) | 12 126 (69.2) | 1.00 (0.98, 1.03) |
 Fungi | 1043 (2.9) | 478 (2.7) | 1.08 (0.97, 1.21) |
Site of infectionb | |||
 Respiratory system | 24 476 (26.2) | 10 700 (23.7) | 1.11 (1.08, 1.13) |
 Genitourinary tract | 17 462 (18.7) | 11 055 (24.5) | 0.76 (0.75, 0.78) |
 Abdomen | 12 294 (13.2) | 3884 (8.6) | 1.53 (1.47, 1.58) |
 Procedure- related | 9448 (10.1) | 4160 (9.2) | 1.10 (1.06, 1.14) |
 Soft tissue | 3483 (3.7) | 1802 (4.0) | 0.93 (0.88, 0.99) |
 Central nervous system | 991 (1.1) | 434 (1.0) | 1.10 (0.98, 1.24) |
 Cardiovascular system | 884 (1.0) | 398 (0.9) | 1.07 (0.95, 1.21) |
 Others/not specified | 35 257 (37.8) | 17 581 (39.0) | 0.97 (0.95, 0.99) |
Organ system dysfunction (number of organs) | |||
 1 | 27 222 (29.1) | 17 392 (38.5) | 0.76 (0.74, 0.77) |
 2 | 30 393 (32.6) | 11 601 (25.7) | 1.26 (1.24, 1.29) |
  > 2 | 35 765 (38.3) | 6457 (14.3) | 2.68 (2.61, 2.75) |
 Not specifiedc | Not applicable | 9687 (21.5) | Not applicable |
 Type of organ system dysfunctionb | |||
 Cardiovascular | 93 380 (100) | 3755 (8.3) | 12.0 (11.63, 12.42) |
 Respiratory | 47 490 (50.9) | 21 190 (47.0) | 1.08 (1.07, 1.10) |
 Renal | 38 789 (41.5) | 21 403 (47.4) | 0.88 (0.86, 0.89) |
 Haematological | 12 220 (13.1) | 5080 (11.3) | 1.16 (1.13, 1.20) |
 Metabolic | 9418 (10.1) | 3978 (8.8) | 1.14 (1.10, 1.19) |
 Neurological | 7083 (7.6) | 4149 (9.2) | 0.83 (0.79, 0.86) |
 Hepatic | 5197 (5.6) | 2490 (5.5) | 1.00 (0.96, 1.06) |
Invasive therapeutic measures | |||
 Mechanical ventilation | 30 569 (32.7) | 7881 (17.5) | 1.88 (1.83, 1.92) |
 Haemodialysis | 9052 (9.7) | 2647 (5.9) | 1.65 (1.58, 1.73) |
In-hospital death | 50 993 (54.6) | 24 502 (54.3) | 1.00 (0.99, 1.02) |