From: Noninvasive ventilation for avoidance of reintubation in patients with various cough strength
Cough peak flow ≤70 L/minute | Cough peak flow >70 L/minute | ||||||
---|---|---|---|---|---|---|---|
NIV (n = 108) | Control (n = 72) | p Valuea | NIV (n = 71) | Control (n = 105) | p Valuea | p Valueb | |
Duration of ICU stay, days | 13 (10–20) | 15 (9–26) | 0.34 | 12 (8–18) | 9 (5–12) | <0.01c | <0.01c |
Duration of hospital stay, days | 23 (14–37) | 26 (15–48) | 0.16 | 19 (12–28) | 17 (12–26) | 0.40 | <0.01c |
Duration of postextubation ICU stay, days | 6 (4–11) | 7 (3–18) | 0.52 | 5 (3–9) | 3 (1–6) | <0.01c | <0.01c |
Duration of postextubation hospital stay, days | 13 (7–23) | 14 (6–26) | 0.78 | 10 (7–17) | 10 (6–16) | 0.54 | <0.01c |
Reintubation at 72 h postextubation | 10 (9 %) | 25 (35 %) | <0.01c | 4 (6 %) | 6 (6 %) | >0.99 | <0.01c |
Reintubation at 7 days postextubation | 26 (24 %) | 35 (49 %) | <0.01c | 6 (9 %) | 9 (9 %) | >0.99 | <0.01c |
Hospital mortality | 36 (33 %) | 33 (46 %) | 0.12 | 8 (11 %) | 14 (13 %) | 0.82 | <0.01c |
Postextubation 90-day mortality | 46 (43 %) | 44 (61 %) | 0.02c | 15 (21 %) | 16 (15 %) | 0.32 | <0.01c |