Fig. 3From: Preoperative plasma growth-differentiation factor-15 for prediction of acute kidney injury in patients undergoing cardiac surgeryReceiver operator characteristics of the Cleveland clinic acute renal failure (CC-ARF) score [13] and nested logistic regression models on the development of cardiac-surgery-associated acute kidney injury (CSA-AKI) with and without taking into account preoperative plasma levels of growth-differentiation factor-15 (GDF). a Analyses for any stage of AKI (i.e., AKI-1 to AKI-3). b Analysis restricted AKI-3 only. The inclusion of GDF in the models led to statistically significant (analysis of variance; p < 0.001) predictive ability (either CC-ARF or a model based on additive Euroscore, age, plasma creatinine, diabetes mellitus, and duration of cardiopulmonary bypass). AUC area under the curveBack to article page