Table 1 Clinical characteristics of the 51 ICU patients enrolled in the study
Characteristic | All (n = 51) | Weaning success (n = 34) | Weaning failure (n = 17) | P value* |
|---|---|---|---|---|
Age (years) | 65 ± 13 | 66 ± 11 | 62 ± 16 | 0.338 |
BMI (kg/m2) | 26 (23–29) | 25 (23–29) | 28 (23–37) | 0.099 |
Male | 31 (61) | 21 (62) | 10 (59) | 0.893 |
Smokers | 21 (41) | 15 (44) | 6 (35) | 0.763 |
SAPS II score on admission | 37 ± 12 | 36 ± 12 | 38 ± 13 | 0.688 |
Comorbidities | ||||
Hypertension | 17 (33) | 10 (29) | 7 (41) | 0.599 |
Coronaropathy | 7 (14) | 4 (12) | 3 (18) | 0.854 |
Diabetes | 10 (20) | 6 (18) | 4 (24) | 0.900 |
Cancer | 7 (14) | 4 (12) | 3 (18) | 0.854 |
COPD | 7 (14) | 4 (12) | 3 (18) | 0.854 |
Type of ICU admission | ||||
Medical | 23 (45) | 14 (41) | 9 (53) | 0.619 |
Urgent surgical | 19 (37) | 13 (38) | 6 (35) | 0.837 |
Elective surgical | 9 (18) | 7 (21) | 2 (12) | 0.697 |
Reason for initiating MV | ||||
Heart failure | 15 (29) | 12 (35) | 3 (18) | 0.328 |
Chronic heart failure | 12 (24) | 9 (26) | 3 (18) | 0.726 |
Myocardial infarction | 3 (6) | 2 (6) | 1 (6) | – |
Sepsis | 21 (42) | 10 (29) | 11 (65) | 0.035 |
Medical sepsis | 12 (24) | 6 (18) | 6 (35) | 0.294 |
Surgical sepsis | 9 (18) | 4 (12) | 5 (29) | 0.163 |
Septic shock | 7 (14) | 4 (12) | 3 (18) | 0.854 |
Other | 15 (29) | 12 (35) | 3 (18) | 0.328 |
Postsurgical respiratory failure | 9 (18) | 6 (18) | 3 (18) | – |
ARDS (moderate) | 6 (12) | 4 (12) | 2 (12) | – |
Treatment received in ICU | ||||
Vasoactive drugs | 14 (27) | 9 (26) | 5 (29) | 0.824 |
Renal replacement therapy | 4 (8) | 3 (9) | 1 (6) | 0.713 |
Aminoglycoside use | 9 (18) | 6 (18) | 3 (18) | – |
Corticosteroids use | 9 (18) | 5 (15) | 4 (24) | 0.697 |
Continuous NMBA administration | 6 (12) | 4 (12) | 2 (12) | – |