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Table 3 Causative pathogens in all unmatched and matched patients with pneumonia stratified according to HIV status

From: Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study

 

Unmatched patients

Matched patients

HIV-positive (n = 30)

HIV-negative (n = 1078)

P

HIV-negative (n = 90)

P

Gram-positive bacteria (%)

8 (26.7)

216 (20)

0.52

18 (20.0)

0.44

Streptococcus pneumoniae (%)

4 (13.3)

71 (6.6)

0.27

5 (5.6)

0.22

Streptococcus species (%)

0

19 (1.8)

0.67

3 (3.3)

0.56

Staphylococcus aureus (%)

4 (13.3)

99 (9.2)

0.52

6 (6.7)

0.27

 Other Gram-positive bacteria (%)

0

27 (2.5)

0.62

4 (4.4)

0.58

Gram-negative bacteria (%)

3 (10.0)

349 (32.4)

0.0075

36 (40.0)

0.011

Haemophilus influenzae (%)

0

70 (6.5)

0.26

9 (10)

0.11

Escherichia coli (%)

1 (3.3)

65 (6)

0.71

5 (5.6)

1

Pseudomonas aeruginosa (%)

0

64 (5.9)

0.25

6 (6.7)

0.33

Klebsiella pneumoniae (%)

1 (3.3)

29 (2.7)

1

3 (3.3)

1

Enterobacter cloacae (%)

0

25 (2.3)

0.63

1 (1.1)

1

Stenotrophomonas maltophilia (%)

1 (3.3)

11 (1)

0.28

1 (1.1)

0.44

 Other Gram-negative bacteria (%)

0

85 (7.9)

0.18

11 (12.2)

0.06

Yeast/fungi (%)

6 (20.0)

84 (7.8)

0.036

18 (20.0)

1

Aspergillus species (%)

1 (3.3)

40 (3.7)

1

9 (10)

0.44

Pneumocystis jirovecii (%)

4 (13.3)

15 (1.4)

0.004

5 (5.6)

0.22

 Other yeasts or fungi (%)

1 (3.3)

29 (2.7)

1

4 (4.4)

1

Viruses (%)

3 (10.0)

70 (6.5)

0.72

10 (11.1)

1

 Influenza (%)

0

38 (3.5)

0.41

8 (8.9)

0.19

 Cytomegalovirus (%)

2 (6.7)

5 (0.5)

0.019

0

0.049

 Other viruses (%)

1 (3.3)

27 (2.5)

1

2 (2.2)

1

Atypical mycobacteria (%)

1 (3.3) a

1 (0.1) b

0.053

0

0.24

Unknown (%)

15 (50)

500 (46.4)

1

30 (33.3)

0.10

  1. Results are presented as number (%). Percentages represent the proportion of pneumonia cases caused by the particular pathogen. Multiple causative pathogens were isolated in some patients with pneumonia. a Mycobacterium avium. b Mycobacterium xenopi