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Table 3 Multivariable linear regression analysis showing the association with admission blood ketone level (mmol/l) in patients not receiving insulin

From: Prevalence of ketosis, ketonuria, and ketoacidosis during liberal glycemic control in critically ill patients with diabetes: an observational study

  Univariable analysis Multivariable analysis
Variable estimate (95 % CI) P value estimate (95 % CI) P value
Blood glucose level, per mmol/l 0.03 (−0.04 to 0.10) 0.35 0.03 (−0.05 to 0.12) 0.44
HbA1c, per % 0.16 (−0.08 to 0.40) 0.18 0.16 (−0.10 to 0.42) 0.21
Blood lactate, per mmol/l 0.02 (−0.08 to 0.12) 0.72 0.05 (−0.08 to 0.19) 0.41
Hematocrit, per % −0.02 (−0.06 to 0.03) 0.38 −0.03 (−0.08 to 0.01) 0.15
Catecholamine infusion
 No Referent   Referent  
 Yes −0.19 (−0.67 to 0.29) 0.43 −0.57 (−1.30 to 0.16) 0.12
Cardiopulmonary bypass surgery
 No Referent   Referent  
 Yes 0.44 (−0.02 to 0.91) 0.06 0.67 (−0.03 to 1.37) 0.06
APACHE III score (tertile)
 23–49 Referent   Referent  
 50–69 −0.68 (−1.23 to −0.13) 0.02 −0.41 (−1.14 to 0.33) 0.27
 70–122 −0.30 (−0.85 to 0.25) 0.28 −0.29 (−0.54 to 1.12) 0.49
  1. HbA1c glycated hemoglobin A1c, APACHE Acute Physiology and Chronic Health Evaluation