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Table 4 Intra-operative risk factors for post-operative delirium

From: Intra-operative events during cardiac surgery are risk factors for the development of delirium in the ICU

Variables included in multivariate analysis

Univariate analysis

Multivariate analysis

AUCROC (95 % CI)

p valuea

OR (95 % CI)

p valueb

Duration of cardiopulmonary bypass

0.73 (0.64–0.83)

<0.001

0.29

Lowest intra-operative MAP, mmHg

0.64 (0.54–0.73)

0.004

0.054

Lowest intra-operative haemoglobin, g/L

0.64 (0.55–0.72)

0.005

0.29

Lowest intra-operative temperature, °C

0.60 (0.50–0.70)

0.035

0.84

Highest noradrenaline dose, μg/kg/minute

0.66 (0.57–0.74)

0.001

0.10

Need for ≥1 RBC transfusion

0.59 (0.49–0.68)

0.063

0.65

Need for ≥1 platelet transfusion

0.65 (0.55–0.74)

0.002

3.9 (1.9–8.0)

<0.001

  1. MAP mean arterial blood pressure, RBC red blood cells
  2. The multivariable analysis (backward logistic regression) revealed that the intra-operative transfusion of one or more bags of platelets was an independent risk factor for the occurrence of delirium after cardiac surgery
  3. a Mann-Whitney U test
  4. b p > 0.05 from variables not in the equation
  5. Bold data indicate significant (p<0.05)