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Fig. 1 | Critical Care

Fig. 1

From: Saline versus balanced solutions: are clinical trials comparing two crystalloid solutions really needed?

Fig. 1

The likely results from a hypothetical randomized clinical trial (RCT) comparing a saline solution with a balanced solution in critically ill patients. Scenario A: saline solutions are discontinued as soon as hyperchloremia appears, thus preventing the harmful effects of a further increase in chloremia and there will likely be no difference in outcomes in the two arms. Scenario B: the administration of saline solutions is continued despite the development of hyperchloremia and the saline group will have worse outcomes than the balanced group

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