Fig. 1

a American Society of Echocardiography (ASE 2009) definition of diastolic dysfunction [15]. The difference in duration flow between atrial reversal of flow and atrial inflow in late diastole duration and change in early diastolic velocity of mitral inflow (E) to late diastolic velocity of mitral inflow (A) with Valsalva were omitted, given the difficulty in acquiring these measurements in this patient population. b Simplified definition of diastolic dysfunction. This is a subset of the parameters presented in the ASE 2009 guidelines. The thresholds used to categorize patients by grade are based on those presented in the ASE guidelines, but have been simplified to include all possible values. Septal e′ early peak velocity of septal mitral annulus, LAVI left atrial volume index, DT mitral deceleration time