Variable | Group | A | B | C | D | p a |
---|---|---|---|---|---|---|
HR (bpm) | Control | 127 ± 25 | 143 ± 16 | 137 ± 15 | 125 ± 20 | |
DEX | 139 ± 14 | 146 ± 27 | 128 ± 32 | 129 ± 30 | ||
MAP (mmHg) | Control | 88 ± 14 | 67 ± 14 | 59 ± 5 | 61 ± 7 | a |
DEX | 99 ± 20 | 63 ± 6 | 62 ± 12 | 58 ± 13 | a | |
CO (ml/kg/min) | Control | 78.3 ± 12.7 | 90.6 ± 26.4 | 80.0 ± 29.5 | 75.1 ± 23.1 | |
DEX | 89.0 ± 27.2 | 109 ± 21.2 | 92.1 ± 28.2 | 72.0 ± 25.9 | ||
MPAP (mmHg) | Control | 14 ± 2 | 20 ± 4 | 23 ± 9 | 23 ± 10 | a |
DEX | 13 ± 3 | 19 ± 7 | 21 ± 6 | 28 ± 5 | a | |
PAOP (mmHg) | Control | 8 ± 1 | 8 ± 1 | 7 ± 1 | 7 ± 1 | |
DEX | 9 ± 3 | 6 ± 2 | 7 ± 2 | 7 ± 3 | ||
SvO2 (%) | Control | 74 ± 4.5 | 78 ± 7.0 | 74 ± 10 | 69 ± 9.3 | |
DEX | 75 ± 5.5 | 77 ± 5.9 | 72 ± 5.9 | 68 ± 12 | ||
P(v-a)CO2 (mmHg) | Control | 4.7 ± 2.9 | 4.4 ± 3.6 | 6.9 ± 4.6 | 5.8 ± 4.0 | |
DEX | 4.1 ± 3.7 | 4.2 ± 1.8 | 3.5 ± 2.0 | 7.1 ± 1.1 | ||
NE (μg/kg/min) | Control | 0.77 ± 0.52 | 1.34 ± 0.6 | 1.88 ± 1.31 | a | |
DEX | 1.08 ± 0.36 | 1.46 ± 0.38 | 1.62 ± 0.45 | a |