Variation in diurnal sedation in mechanically ventilated patients who are managed with a sedation protocol alone or a sedation protocol and daily interruption

Table 4 Variables associated with the patient meeting criteria for a spontaneous breathing trial, multivariable analysis

	Odds ratio	95 % CI		P value
	Odds ratio	lower	upper	P value
Sedation protocol and daily interruption vs sedation protocol alone	0.956	0.685	1.332	0.79
Age (10-year increase)	1.013	0.892	1.151	0.84
Gender (male vs female)	1.039	0.734	1.474	0.83
Surgical/trauma vs medical	0.799	0.441	1.446	0.46
Daytime midazolam dose (1 mg increase)	0.993	0.989	0.997	0.0004
Midazolam: nighttime-daytime dose (1 mg increase)	0.994	0.989	0.998	0.0004
Daytime fentanyl dose (100 mcg increase)	0.940	0.907	0.975	0.0008
Fentanyl: nighttime-daytime dose (100 mcg increase)	0.977	0.938	1.018	0.27

ISSN: 1364-8535