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Table 1 Common causes of failure of weaning trial on day 2

From: Effects of dexmedetomidine and propofol on patient-ventilator interaction in difficult-to-wean, mechanically ventilated patients: a prospective, open-label, randomised, multicentre study

Cause of failure

Number of patients

Dexmedetomidine

Propofol

Respiratory rate >35 breaths/minute

2

4

PaO2ā€‰<65 mmHg with FiO2ā€‰<0.5 or SaO2ā€‰<90 %

1

4

Evident respiratory distress

2

3

Coma, agitation or anxiety

2

3

  1. FiO 2 fraction of inspired oxygen, PaO 2 partial pressure of oxygen, SaO 2 oxygen saturation