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Table 4 Factors associated with ventilator-associated pneumonia by multivariate analysis

From: Hyperoxemia as a risk factor for ventilator-associated pneumonia

Variables

P

OR (95 % CI)

Model 1

  

 SAPS II

0.019

1.01 (1.00, 1.02)*

 Red blood cell transfusion

0.009

1.75 (1.14, 2.70)

 Proton pump inhibitor use

0.040

1.86 (1.03, 3.39)

 Number of days with hyperoxemia

0.001

1.10 (1.04, 1.16)**

Model 2

  

 SAPS II

0.017

1.01 (1.00, 1.02)*

 Red blood cell transfusion

0.009

1.79 (1.16, 2.78)

 Proton pump inhibitor use

0.031

1.92 (1.06, 3.50)

 MV duration prior to VAP

0.012

1.10 (1.01, 1.04)**

 Hyperoxemia at ICU admission

0.004

1.89 (1.23, 2.89)

Model 3

  

 Red blood cell transfusion

0.018

1.71 (1.10, 2.65)

 Proton pump inhibitor use

0.017

2.10 (1.14, 3.79)

 MV duration prior to VAP

0.005

1.03 (1.01, 1.04)*

 Percentage of days with hyperoxemia

0.029

2.20 (1.08, 4.48)**

  1. SAPS simplified acute physiology score; MV mechanical ventilation, VAP ventilator-associated pneumonia. Model 1: *per point of SAPS II, **per day with hyperoxemia; Hosmer-Lemshow goodness-of-fit, p = 0.62. Other non-significant variables included in the model: transfer from other wards, shock, sedation, and duration of MV prior to VAP. Model 2: *per point of SAPS II, **per day of mechanical ventilation; Hosmer-Lemshow goodness-of-fit, p = 0.81. Other non-significant variables included in the model: transfer from other wards, shock, and sedation. Model 3: *per day of mechanical ventilation, **per centile of days with hyperoxemia; Hosmer-Lemshow goodness-of-fit, p = 0.78. Other non-significant variables included in the model: SAPS II, transfer from other wards, shock, and sedation