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Fig. 2 | Critical Care

Fig. 2

From: Decreased CX3CR1 messenger RNA expression is an independent molecular biomarker of early and late mortality in critically ill patients

Fig. 2

Association between chemokine (C-X3-C motif) receptor 1 (CX3CR1) messenger RNA (mRNA) levels at day 1 (D1) or day 3 and early (day 7) or late (day 28) mortality in critically ill patients. CX3CR1 mRNA levels were measured by quantitative real-time polymerase chain reaction in whole-blood samples of a cohort of 725 adult intensive care unit (ICU) patients. The Mann-Whitney U test was used to compare CX3CR1 mRNA levels in survivors versus non-survivors. Kaplan-Meier survival curves were established after stratification based on thresholds defined in ROC curve analyses. A p value <0.05 was considered statistically significant. a CX3CR1 mRNA levels at D1 in ICU patients were significantly different between D7 survivors and non-survivors. b Log-rank test showed that patients with D1 CX3CR1 mRNA levels above the threshold had a significantly better survival than patients with CX3CR1 mRNA levels below the threshold. c CX3CR1 mRNA levels at D3 in ICU patients were significantly different between D28 survivors and non-survivors. d Log-rank test showed that patients with D3 CX3CR1 mRNA levels above the threshold had a significantly better survival than patients with CX3CR1 mRNA levels below the threshold

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