Table 4 Area under the curve (AUC), cutoff and positive predictive value/negative predictive value (PPV/NPV)

From: Adrenomedullin and endothelin-1 are associated with myocardial injury and death in septic shock patients

	Myocardial injury					Mortality at 28 days					Mortality at 7 days
	Cutoff	AUC	Sensitivity	Specificity	PPV/NPV	Cutoff	AUC	Sensitivity	Specificity	PPV/NPV	Cutoff	AUC	Sensitivity	Specificity	PPV/NPV
MR-proADM	4.6 nmol/L	0.729	0.577	0.810	0.79/0.61	3.5 nmol/L	0.730	0.8	0.605	0.44/0.88	5.5 nmol/L	0.823	0.9	0.791	0.5/0.97
CT-proET-1	209 pmol/L	0.855	0.808	0.810	0.81/0.76	206 pmol/L	0.696	0.8	0.579	0.41/0.88	269 pmol/L	0.674	0.7	0.651	0.32/0.90
hsTNT	-	-	-	-	-	114 ng/L	0.752	0.692	0.784	0.53/0.88	114 ng/L	0.74	0.75	0.738	0.35/0.94
APACHE II	-	-	-	-	-	27	0.696	0.667	0.737	0.5/0.88	27	0.744	0.8	0.721	0.4/0.94

MR-proADM mid-regional pro-adrenomedullin, CT-proET-1 C-terminal pro-endothelin-1, hsTNT high-sensitivity troponin T, APACHE acute physiology and chronic health evaluation

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