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Table 4 Area under the curve (AUC), cutoff and positive predictive value/negative predictive value (PPV/NPV)

From: Adrenomedullin and endothelin-1 are associated with myocardial injury and death in septic shock patients

  Myocardial injury Mortality at 28 days Mortality at 7 days
  Cutoff AUC Sensitivity Specificity PPV/NPV Cutoff AUC Sensitivity Specificity PPV/NPV Cutoff AUC Sensitivity Specificity PPV/NPV
MR-proADM 4.6 nmol/L 0.729 0.577 0.810 0.79/0.61 3.5 nmol/L 0.730 0.8 0.605 0.44/0.88 5.5 nmol/L 0.823 0.9 0.791 0.5/0.97
CT-proET-1 209 pmol/L 0.855 0.808 0.810 0.81/0.76 206 pmol/L 0.696 0.8 0.579 0.41/0.88 269 pmol/L 0.674 0.7 0.651 0.32/0.90
hsTNT - - - - - 114 ng/L 0.752 0.692 0.784 0.53/0.88 114 ng/L 0.74 0.75 0.738 0.35/0.94
APACHE II - - - - - 27 0.696 0.667 0.737 0.5/0.88 27 0.744 0.8 0.721 0.4/0.94
  1. MR-proADM mid-regional pro-adrenomedullin, CT-proET-1 C-terminal pro-endothelin-1, hsTNT high-sensitivity troponin T, APACHE acute physiology and chronic health evaluation
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