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Table 4 Multivariable Cox regression analysis of the impact of fluid accumulation on mortality risk in different subgroups (N-AKI, AKI and AKI-RRT)

From: The Dose Response Multicentre Investigation on Fluid Assessment (DoReMIFA) in critically ill patients

 

N-AKI

AKIa

AKI-RRT

 

HR (95 % CI)

p

HR (95 % CI)

p

HR (95 % CI)

p

Unadjusted model

 

 FOSL

1.28 (1.05–1.55)

0.0131

1.26 (1.11–1.44)

0.0005

1.20 (1.05–1.37)

0.0095

Adjusted (selected) modelb

 

 FOSL

1.21 (0.98–1.49)

0.0752

1.31 (1.14–1.50)

0.0001

1.21 (1.04–1.42)

0.0137

  1. Abbreviations: N-AKI patients without AKI, AKI patients with acute kidney injury, AKI-RRT patients with acute kidney injury treated with renal replacement therapy, HR hazard ratio, CI confidence interval, FO SL slope of fluid accumulation
  2. aAKI without RRT
  3. bAdjusted for the same variables as listed in Table 3
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Critical Care

ISSN: 1364-8535