Parameter
|
AKI
|
Non-AKI
|
p
|
---|
Patients/samples (n/n)
|
59/59
|
51/51
| |
Age (years)†
|
65 (45–77)
|
60 (24–77)
|
0.03
|
Gender (female/male)
|
13/46
|
16/35
|
0.29
|
EuroSCORE II** (points)†
|
6.82 (0.86–28.34)
|
5.99 (0.67–21.93)
|
0.89
|
Body mass index†
|
30.7 (19.9–47.3)
|
30.8 (17.3–41.4)
|
0.86
|
S-creatinine at baseline (mg/dL)†
|
1.1 (0.6–1.9)
|
0.9 (0.6–1.3)
|
<0.001
|
Estimated glomerular filtration rate at baseline (mL/h/1.73 m2)‡,†
|
73 (37–110)
|
92 (56–132)
|
<0.001
|
Diabetes (%)
|
29
|
18
|
0.19
|
OP time (min)†
|
214 (105–390)
|
211 (109–651)
|
0.6
|
Time of cardiopulmonary bypass (min)†
|
109 (48–243)
|
103 (34–177)
|
0.81
|
Clamping time (min)†
|
66 (17–184)
|
67 (26–125)
|
0.77
|
Endpoints:
| | | |
NOMI (%)ǁ
|
29
|
2
|
<0.001
|
Death (%)ǁ
|
17
|
0
|
0.002
|
AKI staging (n):
| | | |
0
|
0
|
51
| |
1
|
25
|
0
| |
2
|
14
|
0
| |
3
|
20 (15 w/ hemodialysis)
|
0
| |
-
AKI acute kidney injury, NOMI nonocclusive mesenteric ischemia,
-
**Thoracic Surgeons Risk Score to predict mortality after thoracic surgery, for calculation see: http://www.euroscore.org/
-
‡According to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI)
-
†Given as mean (range)
-
ǁ7 % of AKI patients with composite endpoint