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Table 1 Demographics of flow cytometry cohort

From: Early changes within the lymphocyte population are associated with the development of multiple organ dysfunction syndrome in trauma patients

Demographics

Controls

No MODS

MODS

p value

n

8

19

11

-

% male

100

83

77

0.38

Age

32 (26–35)

35 (27–44)

34 (27–52)

0.71

ISS

1 (1–2)

10 (9–18)

33 (25–50)

<0.01

Base deficit (mmol/L)

−1.9 (−2.3 to −1.0)

−0.5 (−1.4 to −1.6)

3.8 (2.4–7.9)

<0.01

Time of sample from injury (mins)

66 (60–78)

67 (54–75)

85 (70–95)

0.09

CSL pre-draw (ml)

0 (0)

0 (0)

500 (0–500)

<0.01

SBP on arrival (mmHg)

140 (135–149)

139 (131–145)

109 (96–125)

<0.01

Hospital length of stay (days)

2 (1–3)

7 (3–14)

20 (8–39)

0.07

ICU length of stay (days)

0 (0)

0 (0)

8 (2–13)

<0.01

28-day mortality % (n)

0 (0)

0 (0)

31

<0.01

Percentage

    

Lymphocytes

18 (12–24)

18 (12–23)

17 (8–27)

0.95

Total NK cells

16 (7–24)

14 (11–17)

23 (16–29)

0.02

NK bright

0.6 (0.2–1.0)

1.3 (0.4–2.2)

0.8 (0.4–1.1)

0.12

NK dim

15 (7–23)

13 (10–16)

22 (16–28)

<0.01

Gamma delta high

0.7 (0.4–1.0)

1.4 (0.2–2.5)

1.8 (0.0–3.9)

0.86

Gamma delta low

2.1 (1.2–2.9)

4.0 (2.5–5.5)

0.9 (0.5–1.4)

<0.01

T helpers

32 (26–38)

32 (28–36)

35 (29–41)

0.28

Cytotoxic T cells

23 (18–27)

28 (23–33)

21 (17–25)

0.16

Cell count × 109/L

    

Lymphocytes

2.0 (1.3–3.2)

1.4 (0.4–5.1)

2.5 (1.7–3.6)

0.80

Total NK cells

0.2 (0.1–0.6)

0.5 (0.2–0.7)

0.6 (0.2–0.9)

0.14

NK bright

0.01 (0.01–0.02)

0.03 (0.01–0.05)

0.02 (0.01–0.03)

0.20

NK dim

0.2 (0.1–0.5)

0.4 (0.2–0.6)

0.5 (0.2–0.8)

0.12

Gamma delta high

0.01 (0.01–0.03)

0.04 (0.00–0.09)

0.06 (0.00–0.16)

0.73

Gamma delta low

0.03 (0.01–0.08)

0.09 (0.06–0.12)

0.02 (0.01–0.03)

<0.01

T helpers

0.6 (0.4–0.8)

0.9 (0.7–1.1)

0.7 (0.5–0.9)

0.08

Cytotoxic T cells

0.4 (0.3–0.7)

0.8 (0.6–1.0)

0.5 (0.3–0.7)

0.46

  1. p values compare no MODS vs MODS, using Student’s t test
  2. MODS multiple organ dysfunction syndrome, ISS Injury Severity Score, CSL intravenous crystalloid fluid, SBP systolic blood pressure, ICU intensive care unit, NK natural killer
  3. Median (interquartile range)
  4. Mean (95 % confidence interval)