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Fig. 2 | Critical Care

Fig. 2

From: Inflammasome and toll-like receptor signaling in human monocytes after successful cardiopulmonary resuscitation

Fig. 2

Monocyte toll-like receptor (TLR)2, interleukin-1 receptor-associated kinase (IRAK)3, IRAK4, NLR family pyrin domain containing (NLRP)3, and caspase (CASP)1 mRNA expression of survivors and nonsurvivors after cardiac arrest. Monocyte mRNA expression levels of TLR2 (a), IRAK3 (b), IRAK4 (c), NLRP3 (d), and CASP1 (e) in 30-day survivors (n = 12) and nonsurvivors (n = 11) after 48 h after return of spontaneous circulation (ROSC). The 30-day nonsurvivors had significantly lower monocyte TLR2 (p = 0.003), IRAK3 (p = 0.027), IRAK4 (p = 0.027), NLRP3 (p = 0.006), and CASP1 (p = 0.019) mRNA levels after 48 h after ROSC (p = 0.003). Statistical hypothesis testing was performed using the Mann–Whitney U test. RCN relative copy number

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Critical Care

ISSN: 1364-8535