Fig. 1

Monocyte toll-like receptor (TLR) and inflammasome mRNA expression in patients who had experienced cardiac arrest and the control group. Shown are monocyte mRNA expression levels of TLR2 (a), TLR4 (b), interleukin-1 receptor-associated kinase (IRAK)3 (c), IRAK4 (d), NLR family pyrin domain containing (NLRP)1 (e), NLRP3 (f), absent in melanoma (AIM)2 (g), PYD and CARD domain containing (PYCARD) (h), caspase 1 (CASP1) (i), and IL1B (j), expressed as mean relative copy numbers (RCN) and standard deviation, from patients after cardiopulmonary resuscitation (CPR) in the first 12 h (CPR t1; n = 30), after 24 h (CPR t2; n = 29) and 48 h (CPR t3; n = 23) following return of spontaneous circulation, and mRNA expression levels in the control group (coronary artery disease (CAD); n = 19). Statistical hypothesis testing was performed using the Kruskal-Wallis test and post-hoc analysis with all-pairwise comparison using the Dunn-Bonferroni approach (*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001).