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Table 2 Validity values of skin and NC culture and superficial culture (skin + hubs) for prediction of catheter colonization and C-RBSI

From: Vascular catheter colonization: surveillance based on culture of needleless connectors

CULTURE S%
95% CI
SP%
95% CI
PPV%
95% CI
NPV%
95% CI
Validity index
95% CI
Prevalence
95% CI
LR+
95% CI
LR-
95% CI
Catheter colonization
Skin+NCs 77.8
(45.0-100)
52.9
(38.3-67.6)
22.6
(6.2-38.9)-
93.1
(82.2-100)
56.7
(43.3-70.0)
15.0
(5.1-24.9)
1.65
(1.05-2.60)
0.42
(0.12-1.46)
Skin+hubs 66.7
(30.3-100)
86.3
(75.8-92.0)
46.1
(15.2-77.1)
93.6
(85.6-100)
83.3
(73.0-93.6)
15.0
(5.1-24.9)
4.86
(2.12-11.13)
0.39
(0.15-0.98)
C-RBSI
Skin+NCs 100
(75.0-100)
50.0
(36.3-63.7)
6.4
(0.0-16.7)
100
(98.3-100)
51.7
(38.2-65.1)
3.3
(0.0-8.7)
2.00
(1.55-2.59)
NA
Skin+hubs 100
(75.00-100)
81.0
(70.0-91.9)
15.4
(0.0-38.8)
100
(98.9-100)
76.8
(67.0-86.6)
3.3
(0.0-8.7)
5.27
(3.10-8.98)
NA
  1. S, sensitivity; SP, specificity; PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; CI, confidence interval; NA, not applicable; C-RBSI, catheter-related bloodstream infection