| |
Candida spp colonization
|
|---|
|
NCI
|
LGCC
|
HGCC
|
IAC
|
Candidemia
|
P
|
|---|
|
N = 48
|
N = 130
|
N = 24
|
N = 20
|
N = 11
| |
|---|
|
BDG ≥ 80 pg/mL, no. (%)
|
16/46 (34.8)a
|
50/124 (40.3)a
|
17/24 (70.8)b
|
15/20 (75.0)b
|
8/10 (80.0)b
|
< .001
|
|
BDG ≥ 100 pg/mL, no. (%)
|
16/46 (34.8)a
|
45/125 (36.0)a
|
14/24 (58.3)a,b
|
13/20 (65.0)b
|
8/10 (80.0) b
|
.004
|
|
BDG ≥ 200 pg/mL, no. (%)
|
10/47 (21.3)a
|
20/128 (15.6)a
|
11/24 (45.8)b
|
10/20 (50.0)b
|
8/10 (80.0)b
|
< .001
|
|
CAGTA positive, no. (%)
|
10/47 (21.3)a
|
44/128 (34.4)a
|
17/24 (70.8)b
|
8/20 (40.0)a,b
|
8/10 (80.0)b
|
< .001
|
|
Mannan-Ag positive, no. (%)
|
10/48 (20.8)a
|
40/127 (31.5)a
|
15/24 (62.5)b
|
8/20 (40.0)a,b
|
5/10 (50.0)a,b
|
.007
|
|
Mannan-Ab positive, no. (%)
|
6/48 (12.5)
|
12/128 (9.4)
|
4/24 (16.7)
|
5/20 (25.0)
|
3/11 (27.3)
|
.126
|
|
C-PCR positive, no. (%)
|
14/23 (60.9)
|
37/54 (68.5)
|
6/8 (75.0)
|
12/14 (85.7)
|
9/11(81.8)
|
.525
|
- Values are frequencies and percentages. Different superscripts (a,b) indicate nominally significant differences (P < 0.05). Biomarker positives: two determinations consecutives positives (≥ cutoff). C-PCR positive: one determination positive
-
NCI neither colonized nor infected, LGCC low-grade Candida spp. colonization, HGCC high-grade Candida spp. colonization, IAC intra-abdominal candidiasis, BDG (1-3)-ß-D-glucan, CAGTA Candida albicans germ tube antibody, mannan-Ag mannan antigen, mannan-Ab mannan antibody, C-PCR PCR-based Candida detection
