Fig. 2From: Anemia management after acute brain injuryIn the injured brain, cerebral blood flow (CBF, black line) is lower than in the normal brain at the corresponding Hb levels. As the “cerebrovascular reserve” is compromised in this setting, the maximal CBF (CBF max ) will be possibly obtained at Hb levels around 8–9 g/dl and any further decrease of Hb below these thresholds will contribute to reduce cerebral oxygen delivery (DO 2 , grey line). The oxygen extraction rate (OER) then increases to meet metabolic tissue requirements above these thresholdsBack to article page