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Table 1 Albumin and fluid balance during four perioperative time periods in patients (n = 10) subjected to major abdominal surgery, and given starch as part of the perioperative fluid treatment

From: Leakage of albumin in major abdominal surgery

 

Day of surgery, until EOS

EOS until POD 1 06:00

POD 1 until POD 2 06:00

POD 2 until POD 3 06:00

Albumin (g)

    

 Albumin lossa

–15.4 (–8.9; –45.9)

–4.1 (–0.9; –23.1)

–7.9 (–1.7; –16.9)

–4.7 (–0.9; -14.4)

 Albumin infused

0 (0; 15.7)

0 (0; 17.0)

0 (0; 40)

0 (0; 40)

 Albumin balance

–14.0 (–35.4; –1.6)

–3.3 (–11.8; 3.8)

–6.3 (–16.9; 30.7)

–3.0 (–11.1; 33.1)

Fluids (liters)

    

 Blood lossa

1.13 (0.48; 4.50)

0.30 (0.05; 1.59)

0.61 (0.13; 1.30)

0.46 (0.05; 1.31)

 Urine

0.70 (0.13; 3.10)

0.87 (0.38; 1.66)

2.17 (1.15; 3.80)

2.54 (1.60; 4.92)

 Sum of fluid losses

2.41 (0.61; 5.22)

1.45 (0.43; 2.32)

2.59 (1.53; 4.32)

3.05 (1.98; 5.48)

 Albumin and blood products

0.13 (0; 1.53)

0 (0; 1.15)

0 (0; 0.49)

0 (0; 0.48)

 Crystalloids + Glucose

2.60 (1.51; 3.76)

2.81 (1.01; 4.78)

2.80 (1.30; 4.37)

1.95 (1.00; 3.00)

 Starchb

1.90 (0.60; 2.76)

0.63 (0; 1.03)

0.50 (0; 1.50)

0.50 (0; 1.00)

 Sum of infusions

4.93 (2.11; 6.00)

3.87 (1.68; 5.55)

3.55 (1.50; 5.87)

2.37 (1.18; 4.50)

 Fluid balancec

2.21 ± 0.81

2.22 ± 1.26

0.94 ± 1.55

–0.78 ± 1.47

  1. Values are presented as median (range) or mean ± standard deviation, as appropriate
  2. aAlbumin and blood losses estimated from bleeding in suction bottles, sponges, and postoperatively in drains
  3. bMacrodex is included in this volume used after vascular surgery in three patients amounting to 10 % of that volume
  4. cPerspiration from wound, sweat, and breath is ignored
  5. EOS end of surgery, POD postoperative day