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Table 1 Patient and surgical characteristics

From: Effect of hemoadsorption during cardiopulmonary bypass surgery – a blinded, randomized, controlled pilot study using a novel adsorbent

 

HA (n = 19)

Control (n = 18)

OR (95 % CI)

P value

Preoperative characteristics

 Age, years

64 (30–81)

69 (51–81)

 

0.1737

 Male

12

14

0.50 (0.09, 2.56)

0.4756

 Female

7

4

 BMI, kg/m2

27 (18–35)

27 (20–39)

 

0.6593

 EuroSCORE

4.0 ± 3.6

6.0 ± 4.6

 

0.154

 Resistance

411.7 ± 210.2

442.7 ± 101.6

 

0.6948

 Phase angle

5.1 ± 1.5

4.9 ± 0.7

 

0.7078

 TBW

56.3 ± 14.1

46.6 ± 11.3

 

0.1205

 MCI

0

0

 

1

 Asthma

0

0

 

1

 COPD

3

3

0.94 (0.11–8.15)

1

 NIDDM

6

4

1.60 (0.30–9.56)

0.714

 IDDM

0

2

0 (0, 4.99)

0.2297

 CKD

0

0

 

1

 Cardiac decompensation

2

1

1.96 (0.09–124.72)

1

 PAOD

3

1

3.10 (0.22–176.81)

0.6039

 Art. hypertension

10

10

0.89 (0.20–3.90)

1

 Dialysis

0

0

 

1

 Angina pectoris (absence of)

16

13

 

0.5392

 Angina pectoris (stable)

3

4

 

 Angina pectoris (instable)

0

1

 

 LVEF >50 %

12

13

 

0.4756

 LVEF 30–50 %

7

4

 

 LVEF <30 %

0

1

 

Intraoperative characteristics

 Valve procedure, M/F

7/4

7/4

 

0.4819

 CABG, M/F

2/1

5/0

 

 Combined procedure, M/F

3/2

2/0

 

 Anesthesia time, min

474 (290–673)

427 (277–570)

 

0.1683

 Surgery time, min

369 (219–630)

327 (225–493)

 

0.2152

 CPB time, min

191 (112–288)

170 (83–274)

 

0.2064

 AoCC time, min

138 (57–242)

117 (36–179)

 

0.1423

 Fibrinogen, g

1.7 (0–5)

0.8 (0–4)

 

0.077

 Thrombocytes, units

0.15 (0–1)

0.2 (0–1)

 

0.6304

 PCC, IE

605 (0–2000)

389 (0–3000)

 

0.415

 FFP, units

0.5 (0–9)

0

 

0.3306

 Erythrocytes, units

1.4 (0–7)

0.7 (0–3)

 

0.2021

 Cristalloids, ml

5239 ± 1569

4311 ± 1230

 

0.0526

 Colloids, ml

571 ± 327

514 ± 130

 

0.4873

 Diuresis

826 ± 352

978 ± 589

 

0.3516

Postoperative characteristics

 LOS-ICU, days

2.3 ± 2.0

2.4 ± 1.9

 

0.8721

 Mechanical ventilation, days

0.7 ± 1.6

0.2 ± 0.4

 

0.19

 Balance 1POD

9374 ± 4785

7303 ± 2664

 

0.1124

 vaECMO, n

2

0

 

0.4865

 30-day mortality

1

0

 

1

  1. Values are presented as number (n), percentage (%), mean (range), mean ± standard deviation (SD), or odds ratio (95 % confidence interval). The listed P values of statistical tests were calculated by using t test for continuous and the Fisher’s exact test for categorical variables. Abbreviations: AP, angina pectoris; aHTN, arterial hypertension; AoCC, aortic cross-clamp; BMI, body mass index; CABG, coronary artery bypass grafting; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CPB, cardiopulmonary bypass; HA, hemoadsorption; IDDM, insulin-dependent diabetes mellitus; LOS-ICU, length of stay in intensive care unit; LVEF, left ventricular ejection fraction; MCI, myocardial infarction; NIDDM, non-insulin-dependent diabetes mellitus; OR, odds ratio; PAOD, peripheral artery occlusive disease; PCC, prothrombin complex concentrate; TBW, total body water; vaECMO, veno-arterial extra corporal membrane oxygenation