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Table 6 Multivariable logistic regression with multiple imputation for analysis of in-hospital mortality in patients undergoing VA-ECMO for cardiogenic shock

From: In-hospital mortality and successful weaning from venoarterial extracorporeal membrane oxygenation: analysis of 5,263 patients using a national inpatient database in Japan

 

Odds ratio

95 % Confidence interval

P value

Age, years

    

 19–39

Reference

   

 40–59

1.08

0.79

1.47

0.65

 60–79

1.64

1.23

2.17

0.001

 ≥ 80

2.61

1.81

3.77

<0.001

Sex

    

 Male

Reference

   

 Female

0.96

0.82

1.12

0.61

Hospital volume per year

    

 0–9

Reference

   

 10–19

0.83

0.68

1.01

0.07

 ≥ 20

0.80

0.63

1.02

0.07

Body mass index, kg/m2

    

 < 18.5

1.28

1.01

1.62

0.04

 18.5–24.9

Reference

   

 ≥ 25.0

1.24

1.04

1.47

0.02

Etiology

    

 Ischemic heart disease

Reference

   

 Heart failure

0.55

0.46

0.65

<0.001

 Valvular disease

0.85

0.66

1.10

0.22

 Myocarditis

0.42

0.31

0.57

<0.001

 Cardiomyopathy

0.75

0.51

1.08

0.12

 Takotsubo cardiomyopathy

0.58

0.27

1.21

0.14

 Infectious endocarditis

0.69

0.21

2.28

0.55

Cardiac arrest

    

 No

Reference

   

 Yes

1.52

1.28

1.82

<0.001

Chronic renal failure

    

 No

Reference

   

 Yes

0.90

0.69

1.16

0.40

Liver failure pre-ECMO

    

 No

Reference

   

 Yes

1.30

0.71

2.38

0.40

Central nervous system dysfunction pre-ECMO

    

 No

Reference

   

 Yes

0.87

0.45

1.70

0.68

Duration of intubation prior to VA-ECMO, days

    

 0

Reference

   

 1

1.03

0.44

2.39

0.94

 ≥ 2

0.47

0.32

0.70

<0.001

Use of intra-aortic balloon pumping

    

 No

Reference

   

 Yes

0.58

0.49

0.68

<0.001

Use of continuous renal replacement therapy

   

 No

Reference

   

 Yes

1.95

1.63

2.33

<0.001

  1. VA-ECMO venoarterial extracorporeal membrane oxygenation