| |
Hydrocortisone (n = 25)
|
Placebo (n = 25)
|
p value
|
|---|
|
Adverse event after study drug
| | | |
|
Any bleeding
|
5 (20 %)
|
2 (9 %)
|
0.42
|
|
New or changed antibiotics
|
9 (36 %)
|
11 (44 %)
|
0.77
|
|
New insulin infusion
|
7 (28 %)
|
6 (24 %)
|
1.00
|
|
Laboratory values
| | | |
|
Glucose level (mg/dL)
| | | |
|
6 hour
|
242 (151)
|
230 (118)
|
0.76
|
|
24 hour
|
218 (109)
|
199 (90)
|
0.54
|
|
48 hour
|
163 (50)
|
155 (59)
|
0.66
|
|
72 hour
|
150 (52)
|
144 (61)
|
0.79
|
|
Sodium level (mmol/L)
| | | |
|
6 hour
|
139 (5)
|
139 (6)
|
0.78
|
|
24 hour
|
139 (5)
|
138 (5)
|
0.37
|
|
48 hour
|
139 (7)
|
139 (5)
|
0.80
|
|
72 hour
|
143 (6)
|
139 (8)
|
0.09
|
|
White blood count (x 103)
| | | |
|
6 hour
|
15.0 (6.9)
|
17.0 (6.7)
|
0.43
|
|
24 hour
|
17.8 (8.7)
|
15.5 (4.7)
|
0.29
|
|
48 hour
|
21.5 (9.3)
|
12.6 (3.4)
|
<0.001
|
|
72 hour
|
19.2 (8.8)
|
11.9 (2.9)
|
0.005
|
-
aCategorical variables are presented as count (frequency) and continues variables as mean (standard deviation)
