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Table 3 Analysis of outcome groupa

From: Piperacillin concentration in relation to therapeutic range in critically ill patients – a prospective observational study

Correlation of piperacillin trough levelsb with CRP levels Number of patients Correlation coefficient p value
Trough level day 1 versus CRP day 1 13 0.13 0.67
Trough levels day 1 + 2 versus CRP day 2 13 - 0.22 0.94
Trough levels day 1 + 2 + 3 versus CRP day 3 12 - 0.31 0.33
Trough levels day 1 + 2 + 3 + 4 versus CRP day 4 11 - 0.66 0.028*
Trough levels day 1 + 2 versus the quotient CRP day 2/1 13 - 0.12 0.71
Trough levels day 1 + 2 + 3 versus the quotient CRP day 3/1 12 - 0.50 0.095
Trough levels day 1 + 2 + 3 + 4 versus the quotient CRP day 4/1 11 - 0.55 0.083
Pathogens of the outcome group Number of pathogens   
Burkholderia multivorans 1   
Citrobacter freundii 1   
Enterococcus faecalis 3   
Klebsiella oxytoca 1   
Klebsiella pneumoniae 1   
Proteus mirabilis 1   
Propionibacterium acnes 3   
Pseudomonas aeruginosa 2   
Pseudomonas oleovorans 1   
Raoultella ornithinolytica 1   
Staphylococcus aureus 4   
Streptococci beta hemolytic group C 1   
Streptococcus anginosus 1   
Streptococcus pneumoniae 1   
Streptococcus viridans 1   
  1. CRP C-reactive protein
  2. aIn this group, only patients with bacterial isolates that met all the following criteria were included: (1) the isolates were clinically assumed to be causative strains for the patients’ infection, (2) all assumed causative strains were bacteria and were sensitive to PIP-TAZ, (3) but not to other antibiotic substances given to the patient
  3. bOnly one piperacillin trough level used per day