TY - JOUR AU - Zander, Johannes AU - Döbbeler, Gundula AU - Nagel, Dorothea AU - Maier, Barbara AU - Scharf, Christina AU - Huseyn-Zada, Mikayil AU - Jung, Jette AU - Frey, Lorenz AU - Vogeser, Michael AU - Zoller, Michael PY - 2016 DA - 2016/04/04 TI - Piperacillin concentration in relation to therapeutic range in critically ill patients – a prospective observational study JO - Critical Care SP - 79 VL - 20 IS - 1 AB - Piperacillin levels after standard dosing have been shown frequently to be subtherapeutic, especially when renal clearance was augmented. Here, we aimed to determine if piperacillin was in its therapeutic range in a typically heterogeneous intensive care unit patient group, and also to describe target attainment dependent on daily dosage, creatinine clearance, and renal replacement therapy (RRT). SN - 1364-8535 UR - https://doi.org/10.1186/s13054-016-1255-z DO - 10.1186/s13054-016-1255-z ID - Zander2016 ER -