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Table 5 Logistic regression of risk factors for recurrence of atrial fibrillation

From: Variable use of amiodarone is associated with a greater risk of recurrence of atrial fibrillation in the critically ill

Variable

OR

95 % CI

P

Univariate regression

 

History congestive cardiac failure

2.84

1.05–7.65

0.04

Peripheral vascular disease

2.06

0.99–4.27

0.05

Cerebrovascular disease

0.40

0.14–1.10

0.07

SIRS

1.77

0.96–3.27

0.07

Ischaemic heart disease

1.71

0.91–3.23

0.10

Mitral valve disease

0.25

0.05–1.26

0.09

Metastatic tumour

3.03

0.79–11.6

0.11

Leukaemia

3.03

0.79-11.61

0.11

Age

1.02

1.00–1.04

0.12

Body mass index

0.96

0.92–1.00

0.06

Concurrent use of beta-blockers

1.50

0.83-2.73

0.18

Concurrent use of digoxin*

5.06

2.20–11.67

<0.001

Ceasing amiodarone while on inotrope infusion

8.76

3.58–21.4

<0.001

Delay of infusion after bolus dose of amiodarone

1.86

1.02–3.44

0.05

Receiving a bolus dose and infusion of amiodarone

0.44

0.23–0.86

0.02

Remaining on amiodarone to discharge from ICU

0.02

0.01–0.05

<0.001

Multivariate regression

 

Ceasing amiodarone while on inotrope infusion

5.89

1.86–18.6

0.003

Remaining on amiodarone for duration of ICU admission

0.01

0.003–0.04

<0.001

SIRS

4.21

1.32–13.4

0.02

Hosmer and Lemeshow Goodness of Fit Chi2 7.19, P = 0.21

Area under ROC curve (discrimination) 0.92

  1. * All patients receiving digoxin also were on a beta-blocker
  2. CI Confidence interval, ICU intensive care unit, OR odds ratio, ROC receiver operating characteristic, SIRS systemic inflammatory response syndrome