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Table 1 Baseline characteristics of the study patientsa

From: Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-blind, placebo-controlled, phase II trial

  Thiamine (n = 31) Placebo (n = 33)
Demographics   
 Age (years) 71 (67, 75) 73 (68, 79)
 Sex (female) 6 (19) 10 (30)
 Body mass index (kg/m2) 29 (26, 33) 28 (25, 29)
 Race   
 White 31 (100) 32 (97)
 Black 0 (0) 1 (3)
EuroSCORE II (%) 3.4 (2.1, 5.2) 2.3 (1.9, 4.5)
EuroSCORE II > 4.0 % 9 (29) 12 (36)
Cardiac past medical history   
 MI/PCI 14 (45) 12 (36)
 Atrial fibrillation 7 (23) 5 (15)
 Previous cardiac surgery 0 (0) 2 (6)
 Chronic heart failure 4 (13) 8 (24)
 Valve disease 12 (39) 8 (24)
Ejection fraction (%) 53 (40, 60) 55 (45, 60)
Current NYHA classb   
 I 5 (16) 1 (3)
 II 12 (29) 14 (42)
 III 14 (45) 15 (45)
 IV 0 (0) 3 (9)
Current angina classb   
 No symptoms 13 (42) 14 (42)
 I 0 (0) 1 (3)
 II 3 (10) 5 (15)
 III 7 (23) 7 (21)
 IV 8 (26) 8 (18)
Other past medical history   
 Pulmonary disease 3 (10) 5 (15)
 Diabetes 14 (45) 14 (42)
  Insulin dependent 7 (50) 6 (43)
  Non-insulin dependent 7 (50) 8 (57)
 Renal disease 7 (23) 11 (33)
 Cancer 1 (3) 2 (6)
Pre-operative laboratory values   
 White blood count (×103) 8.2 (6.8, 8.9) 7.5 (5.7, 10.0)
 Hemoglobin (g/dL) 12.9 (11.5, 14.4) 13.0 (11.2, 14.2)
 Creatinine (mg/dL) 1.1 (0.8, 1.6) 1.1 (0.8, 1.3)
 Glucose (mg/dL) 131 (108, 164) 114 (94, 145)
Pre-surgical characteristics   
 Status   
  Elective 14 (45) 12 (36)
  Urgent 17 (55) 21 (65)
 Location prior to surgery   
  Home 13 (42) 9 (27)
  Ward 15 (48) 24 (73)
  Intensive care unit 3 (10) 0 (0)
  1. Abbreviations: EuroSCORE European System for Cardiac Operative Risk Evaluation, MI myocardial infarction, PCI percutaneous coronary intervention, NYHA New York Heart Association
  2. aCategorical variables are presented as count (frequency) and continuous variables as median (quartiles)
  3. bDefined as the worst classification within the last 2 weeks