| Thiamine (n = 31) | Placebo (n = 33) |
---|---|---|
Demographics | Â | Â |
 Age (years) | 71 (67, 75) | 73 (68, 79) |
 Sex (female) | 6 (19) | 10 (30) |
 Body mass index (kg/m2) | 29 (26, 33) | 28 (25, 29) |
 Race |  |  |
 White | 31 (100) | 32 (97) |
 Black | 0 (0) | 1 (3) |
EuroSCORE II (%) | 3.4 (2.1, 5.2) | 2.3 (1.9, 4.5) |
EuroSCORE II > 4.0 % | 9 (29) | 12 (36) |
Cardiac past medical history | Â | Â |
 MI/PCI | 14 (45) | 12 (36) |
 Atrial fibrillation | 7 (23) | 5 (15) |
 Previous cardiac surgery | 0 (0) | 2 (6) |
 Chronic heart failure | 4 (13) | 8 (24) |
 Valve disease | 12 (39) | 8 (24) |
Ejection fraction (%) | 53 (40, 60) | 55 (45, 60) |
Current NYHA classb | Â | Â |
 I | 5 (16) | 1 (3) |
 II | 12 (29) | 14 (42) |
 III | 14 (45) | 15 (45) |
 IV | 0 (0) | 3 (9) |
Current angina classb | Â | Â |
 No symptoms | 13 (42) | 14 (42) |
 I | 0 (0) | 1 (3) |
 II | 3 (10) | 5 (15) |
 III | 7 (23) | 7 (21) |
 IV | 8 (26) | 8 (18) |
Other past medical history | Â | Â |
 Pulmonary disease | 3 (10) | 5 (15) |
 Diabetes | 14 (45) | 14 (42) |
  Insulin dependent | 7 (50) | 6 (43) |
  Non-insulin dependent | 7 (50) | 8 (57) |
 Renal disease | 7 (23) | 11 (33) |
 Cancer | 1 (3) | 2 (6) |
Pre-operative laboratory values | Â | Â |
 White blood count (×103) | 8.2 (6.8, 8.9) | 7.5 (5.7, 10.0) |
 Hemoglobin (g/dL) | 12.9 (11.5, 14.4) | 13.0 (11.2, 14.2) |
 Creatinine (mg/dL) | 1.1 (0.8, 1.6) | 1.1 (0.8, 1.3) |
 Glucose (mg/dL) | 131 (108, 164) | 114 (94, 145) |
Pre-surgical characteristics | Â | Â |
 Status |  |  |
  Elective | 14 (45) | 12 (36) |
  Urgent | 17 (55) | 21 (65) |
 Location prior to surgery |  |  |
  Home | 13 (42) | 9 (27) |
  Ward | 15 (48) | 24 (73) |
  Intensive care unit | 3 (10) | 0 (0) |