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Table 3 Adjusted Cox proportional hazard model of liver parameters beforre ECMO implantation

From: Liver function predicts survival in patients undergoing extracorporeal membrane oxygenation following cardiovascular surgery

  

30-day mortality

Long-term mortality

 

Baseline parameters

SD

Adjusted HR (95 % CI)

P value

Adjusted HR (95 % CI)

P value

Alkaline phosphatase, U/L

68.9

1.36 (1.10–1.68)

0.004

1.27 (1.03–1.56)

0.023

Bilirubin total, mg/dl

2.0

1.22 (1.07–1.40)

0.004

1.22 (1.07–1.39)

0.003

Aspartate transaminase, U/L

303.5

1.07 (0.90–1.27)

0.44

1.05 (0.91–1.22)

0.48

Alanine transaminase, U/L

192.0

1.11 (0.93–1.33)

0.27

1.08 (0.93–1.26)

0.30

AST/ALT ratio, n

1.9

0.90 (0.70–1.17)

0.43

0.89 (0.74–1.08)

0.24

γ-Glutamyl transferase, U/L

133.3

1.09 (0.87–1.35)

0.47

1.12 (0.95–1.31)

0.18

Albumin, g/L

8.7

0.81 (0.65–1.01)

0.06

0.83 (0.71–0.98)

0.028

Normotest, %

30.0

1.03 (0.81–1.31)

0.81

1.06 (0.88–1.26)

0.56

  1. ALT alanine aminotransferase, AST aspartate aminotransferase, CI confidence interval, HR hazard ratio, SD, standard deviation
  2. Hazard ratios refer to a 1-SD increase and/or decrease in continuous variables. HRs are adjusted for all variables in the clinical confounder model (i.e., for age, sex, Simplified Acute Physiology Score-3, left ventricular function, hypertension, diabetes, estimated glomerular filtration rate, type of cardiovascular surgery, and year of study enrollment.
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