Skip to main content

Table 3 Adjusted Cox proportional hazard model of liver parameters beforre ECMO implantation

From: Liver function predicts survival in patients undergoing extracorporeal membrane oxygenation following cardiovascular surgery

   30-day mortality Long-term mortality  
Baseline parameters SD Adjusted HR (95 % CI) P value Adjusted HR (95 % CI) P value
Alkaline phosphatase, U/L 68.9 1.36 (1.10–1.68) 0.004 1.27 (1.03–1.56) 0.023
Bilirubin total, mg/dl 2.0 1.22 (1.07–1.40) 0.004 1.22 (1.07–1.39) 0.003
Aspartate transaminase, U/L 303.5 1.07 (0.90–1.27) 0.44 1.05 (0.91–1.22) 0.48
Alanine transaminase, U/L 192.0 1.11 (0.93–1.33) 0.27 1.08 (0.93–1.26) 0.30
AST/ALT ratio, n 1.9 0.90 (0.70–1.17) 0.43 0.89 (0.74–1.08) 0.24
γ-Glutamyl transferase, U/L 133.3 1.09 (0.87–1.35) 0.47 1.12 (0.95–1.31) 0.18
Albumin, g/L 8.7 0.81 (0.65–1.01) 0.06 0.83 (0.71–0.98) 0.028
Normotest, % 30.0 1.03 (0.81–1.31) 0.81 1.06 (0.88–1.26) 0.56
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, CI confidence interval, HR hazard ratio, SD, standard deviation
  2. Hazard ratios refer to a 1-SD increase and/or decrease in continuous variables. HRs are adjusted for all variables in the clinical confounder model (i.e., for age, sex, Simplified Acute Physiology Score-3, left ventricular function, hypertension, diabetes, estimated glomerular filtration rate, type of cardiovascular surgery, and year of study enrollment.