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Table 1 Baseline characteristics of total ECMO study population (n = 240)

From: Liver function predicts survival in patients undergoing extracorporeal membrane oxygenation following cardiovascular surgery

Characteristics Total study population (n = 240)
Baseline characteristics at hospital admission
 Age, years, median (IQR) 65 (55–72)
 Male sex, n (%) 172 (72)
 EuroSCORE (additive), points (IQR) 10 (8–13)
 Procedure duration, h:min (IQR) 8:00 (6:08–9:37)
 Hypertension, n (%) 169 (70)
 Diabetes, n (%) 66 (28)
 Hypercholesterolemia, n (%) 125 (52)
 Coronary artery disease, n (%) 124 (52)
Left ventricular ejection fraction
 30–44 %, n (%) 35 (15)
  < 30 %, n (%) 94 (39)
Creatinine, mg/dl (IQR) 1.3 (1.1–1.8)
eGFR, ml/min/1.73 m2 (IQR) 51.3 (38.9–68.5)
Blood urea nitrogen, mg/dl (IQR) 24.2 (18.2–36.1)
Cholesterol, mg/dl (IQR) 143 (104–182)
C-reactive protein, mg/dl (IQR) 1.0 (0.3–4.3)
White blood cells, g/L (IQR) 8.0 (6.1–11.1)
Thrombocytes, G/L (IQR) 188 (134–241)
Liver parameters
 Bilirubin total, mg/dl (IQR) 1.1 (0.6–1.6)
 Alkaline phosphatase, U/L (IQR) 81 (61–110)
 Aspartate transaminase, U/L (IQR) 33 (23–67)
 Alanine transaminase, U/L (IQR) 27 (18–47)
 AST/ALT ratio, n (IQR) 1.3 (0.9–2.1)
 γ-Glutamyl transferase, U/L (IQR) 54 (32–105)
 Albumin, g/L (IQR) 38.6 (30.8–42.4)
 Normotest, % (IQR) 75 (50–94)
Post-ECMO implantation (first 24 h)
 SAPS-3, n (%) 43 (36–51)
 SOFA score, n (IQR) 12 (10–14)
 ECMO flow, L/min (IQR) 3.36 (2.50–4.25)
 ECMO rotation, rpm (IQR) 3000 (2485–3500)
 ECMO gas flow, L/minute (IQR) 2.5 (2.0 − 3.0)
 ECMO FiO2, % (IQR) 70 (60–100)
 ECMO duration, days, median (IQR) 4 (3–7)
Hemodynamic parameters (at ICU admission)
 Mean arterial pressure, mmHg (IQR) 72 (65–79)
 Cardiac output, L/minute 3.9 (2.8–5.1)
 ScVO2, % (IQR) 71 (64–77)
 Central venous pressure, mmHg (IQR) 14 (11–16)
Medication (first 24 h post-ECMO)
 Noradrenaline, n (%) 234 (98)
 Noradrenaline (maximum dose), μg/kg/minute 0.28 (0.13–0.58)
 Dobutamine, n (%) 218 (91)
 Dobutamine (maximum dose), μg/kg/minute 4.78 (2.88–7.14)
 Vasopressin, n (%) 85 (35)
 Vasopressin (maximum dose), U/h (IQR) 3.0 (2.0–4.0)
  1. ALT alanine aminotransferase, AST aspartate aminotransferase, ECMO extracorporeal membrane oxygenation, eGFR estimated glomerular filtration rate, EuroSCORE European System for Cardiac Operative Risk Evaluation, FiO 2 fraction of inspired oxygen, ICU intensive care unit, IQR interquartile range, SAPS Simplified Acute Physiology Score, ScVO 2 central venous oxygen saturation, SOFA Sequential Organ Failure Assessment