Skip to main content

Advertisement

Table 2 Influence of the 24-h ANG2/ANG1 ratio

From: Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance

Variable ANG2/ANG1 ANG2/ANG1 p value
<0.18 >0.18
Details of patients and procedure
 Preoperative ejection fraction, % 60 (53–67) 50 (44–55) 0.01
 CPB time, minutes 113 (90–125) 110 (103–125) 0.49
 Aortic cross-clamp/reperfusion time, minutes 105 (85–120) 105 (93–115) 0.9
Postoperative details (T24)
 PaO2/FiO2 ratio 407 (360–502) 429 (182–481) 0.79
 Lactate, mmol/l 1.27 (1–1.4) 1.32 (1.1–1.2) 0.68
 Hgb, mmol/l 9.7 (9.3–10.4) 10.2 (9.1–11.6) 0.52
 Crystalloid fluid balance, ml 3100 (2340–3735) 4830 (3310–5720) 0.01
 Serum creatinine, mg/dl 1.03 (0.9–1.12) 0.98 (0.74–1.19) 0.58
 Duration of mechanical ventilation, h 16.5 (10.3–18.9) 18.8 (17.1–20.2) 0.12
 ICU LOS, h 22.2 (21–35.4) 44.4 (21.3–74.6) 0.2
 LOS hospital, days 14 (9–15) 14 (11–21) 0.12
  1. The study population was divided into two groups according to the angiopoietin (ANG)2/ANG1 ratio measured 24 h after aortic de-clamping using the overall median ratio (0.18) as threshold value. Details are presented for patients, procedures, and postoperative variables recorded 24 h after admission to ICU (T 24 ). Median with percentile 25–75, two-tailed Mann–Whitney test. CPB cardiopulmonary bypass, PaO 2 arterial oxygen partial pressure, FiO 2 inspiratory oxygen fraction, Hgb hemoglobin, ICU LOS length of stay on intensive care unit, LOS hospital length of stay in hospital