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Fig. 2 | Critical Care

Fig. 2

From: Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance

Fig. 2

Changes in angiopoietin and TIE2 serum levels upon coronary artery bypass graft (CABG). Serum was sampled from patients being scheduled for elective on-pump CABG before surgery (preop) and 1, 6 and 24 h after closure of the aortic clamp. Serum was analyzed for angiopoietin 1 (ANG1) (a), ANG2 (b) and soluble TIE2 receptor (sTIE2) (d) by enzyme-linked immunosorbent assay. Furthermore, the ANG2/ANG1 ratio was calculated (c). N = 28 (24-h time point, n = 26), median with percentile 25–75, *p <0.05, **p <0.01, ***p <0.001 (vs. preop). CPB cardiopulmonary bypass

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