Fig. 2

Determination of the pattern of expression of specific receptors on CD4⁺ and CD8⁺ T cells. Peripheral blood was collected from eight survivors of sepsis and matched controls and stained for the indicated markers, followed by determination of percent positive relative to isotype control staining (bottom line) and quantification of fluorescence intensity by molecules of equivalent soluble fluorochrome (MESF) calculation (upper line) as described in “Methods”. Each data point represents an individual patient. Horizontal lines indicate median values. PD programmed cell death, BTLA B- and T-lymphocyte attenuator