TY - JOUR AU - Angus, D. C. AU - Linde-Zwirble, W. T. AU - Lidicker, J. AU - Clermont, G. AU - Carcillo, J. AU - Pinsky, M. R. PY - 2001 DA - 2001// TI - Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care JO - Crit Care Med. VL - 29 UR - https://doi.org/10.1097/00003246-200107000-00002 DO - 10.1097/00003246-200107000-00002 ID - Angus2001 ER - TY - JOUR AU - Vincent, J. -. L. AU - Sakr, Y. AU - Sprung, C. L. AU - Ranieri, V. M. AU - Reinhart, K. AU - Gerlach, H. PY - 2006 DA - 2006// TI - Sepsis in European intensive care units: results of the SOAP study JO - Crit Care Med. VL - 34 UR - https://doi.org/10.1097/01.CCM.0000194725.48928.3A DO - 10.1097/01.CCM.0000194725.48928.3A ID - Vincent2006 ER - TY - JOUR AU - Engel, C. AU - Brunkhorst, F. M. AU - Bone, H. -. G. AU - Brunkhorst, R. AU - Gerlach, H. AU - Grond, S. PY - 2007 DA - 2007// TI - Epidemiology of sepsis in Germany: results from a national prospective multicenter study JO - Intensive Care Med. VL - 33 UR - https://doi.org/10.1007/s00134-006-0517-7 DO - 10.1007/s00134-006-0517-7 ID - Engel2007 ER - TY - JOUR AU - Bone, R. C. AU - Balk, R. A. AU - Cerra, F. B. AU - Dellinger, R. P. AU - Fein, A. M. AU - Knaus, W. A. PY - 1992 DA - 1992// TI - Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine JO - Chest VL - 101 UR - https://doi.org/10.1378/chest.101.6.1644 DO - 10.1378/chest.101.6.1644 ID - Bone1992 ER - TY - JOUR AU - Bone, R. C. AU - Grodzin, C. J. AU - Balk, R. A. PY - 1997 DA - 1997// TI - Sepsis: a new hypothesis for pathogenesis of the disease process JO - Chest. VL - 112 UR - https://doi.org/10.1378/chest.112.1.235 DO - 10.1378/chest.112.1.235 ID - Bone1997 ER - TY - JOUR AU - Bone, R. C. PY - 1996 DA - 1996// TI - Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation JO - Crit Care Med. VL - 24 UR - https://doi.org/10.1097/00003246-199601000-00026 DO - 10.1097/00003246-199601000-00026 ID - Bone1996 ER - TY - JOUR AU - Muenzer, J. T. AU - Davis, C. G. AU - Chang, K. AU - Schmidt, R. E. AU - Dunne, W. M. AU - Coopersmith, C. M. PY - 2010 DA - 2010// TI - Characterization and modulation of the immunosuppressive phase of sepsis JO - Infect Immun. VL - 78 UR - https://doi.org/10.1128/IAI.01213-09 DO - 10.1128/IAI.01213-09 ID - Muenzer2010 ER - TY - JOUR AU - Hotchkiss, R. S. AU - Nicholson, D. W. PY - 2006 DA - 2006// TI - Apoptosis and caspases regulate death and inflammation in sepsis JO - Nat Rev Immunol. VL - 6 UR - https://doi.org/10.1038/nri1943 DO - 10.1038/nri1943 ID - Hotchkiss2006 ER - TY - JOUR AU - Monneret, G. AU - Debard, A. -. L. AU - Venet, F. AU - Bohe, J. AU - Hequet, O. AU - Bienvenu, J. PY - 2003 DA - 2003// TI - Marked elevation of human circulating CD4 + CD25+ regulatory T cells in sepsis-induced immunoparalysis JO - Crit Care Med. VL - 31 UR - https://doi.org/10.1097/01.CCM.0000069345.78884.0F DO - 10.1097/01.CCM.0000069345.78884.0F ID - Monneret2003 ER - TY - JOUR AU - Boomer, J. S. AU - Green, J. M. AU - Hotchkiss, R. S. PY - 2014 DA - 2014// TI - The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer? JO - Virulence. VL - 5 UR - https://doi.org/10.4161/viru.26516 DO - 10.4161/viru.26516 ID - Boomer2014 ER - TY - JOUR AU - Otto, G. P. AU - Sossdorf, M. AU - Claus, R. A. AU - Rödel, J. AU - Menge, K. AU - Reinhart, K. PY - 2011 DA - 2011// TI - The late phase of sepsis is characterized by an increased microbiological burden and death rate JO - Crit Care. VL - 15 UR - https://doi.org/10.1186/cc10332 DO - 10.1186/cc10332 ID - Otto2011 ER - TY - JOUR AU - Monneret, G. AU - Venet, F. AU - Kullberg, B. -. J. AU - Netea, M. G. PY - 2011 DA - 2011// TI - ICU-acquired immunosuppression and the risk for secondary fungal infections JO - Med Mycol. VL - 49 UR - https://doi.org/10.3109/13693786.2010.509744 DO - 10.3109/13693786.2010.509744 ID - Monneret2011 ER - TY - JOUR AU - Brenner, T. AU - Rosenhagen, C. AU - Hornig, I. AU - Schmidt, K. AU - Lichtenstern, C. AU - Mieth, M. PY - 2012 DA - 2012// TI - Viral infections in septic shock (VISS-trial)-crosslinks between inflammation and immunosuppression JO - J Surg Res. VL - 176 UR - https://doi.org/10.1016/j.jss.2011.10.020 DO - 10.1016/j.jss.2011.10.020 ID - Brenner2012 ER - TY - JOUR AU - Dellinger, R. P. AU - Levy, M. M. AU - Rhodes, A. AU - Annane, D. AU - Gerlach, H. AU - Opal, S. M. PY - 2013 DA - 2013// TI - Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012 JO - Crit Care Med. VL - 41 UR - https://doi.org/10.1097/CCM.0b013e31827e83af DO - 10.1097/CCM.0b013e31827e83af ID - Dellinger2013 ER - TY - JOUR AU - Boomer, J. S. AU - To, K. AU - Chang, K. C. AU - Takasu, O. AU - Osborne, D. F. AU - Walton, A. H. PY - 2011 DA - 2011// TI - Immunosuppression in patients who die of sepsis and multiple organ failure JO - JAMA. VL - 306 UR - https://doi.org/10.1001/jama.2011.1829 DO - 10.1001/jama.2011.1829 ID - Boomer2011 ER - TY - JOUR AU - Gentile, L. F. AU - Cuenca, A. G. AU - Efron, P. A. AU - Ang, D. AU - Bihorac, A. AU - McKinley, B. A. PY - 2012 DA - 2012// TI - Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care JO - J Trauma Acute Care Surg. VL - 72 UR - https://doi.org/10.1097/TA.0b013e318256e000 DO - 10.1097/TA.0b013e318256e000 ID - Gentile2012 ER - TY - JOUR AU - Winters, B. D. AU - Eberlein, M. AU - Leung, J. AU - Needham, D. M. AU - Pronovost, P. J. AU - Sevransky, J. E. PY - 2010 DA - 2010// TI - Long-term mortality and quality of life in sepsis: a systematic review JO - Crit Care Med. VL - 38 UR - https://doi.org/10.1097/CCM.0b013e3181d8cc1d DO - 10.1097/CCM.0b013e3181d8cc1d ID - Winters2010 ER - TY - JOUR AU - Quartin, A. A. AU - Schein, R. M. AU - Kett, D. H. AU - Peduzzi, P. N. PY - 1997 DA - 1997// TI - Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group JO - JAMA VL - 277 UR - https://doi.org/10.1001/jama.1997.03540370048035 DO - 10.1001/jama.1997.03540370048035 ID - Quartin1997 ER - TY - JOUR AU - Yende, S. AU - Angus, D. C. PY - 2007 DA - 2007// TI - Long-term outcomes from sepsis JO - Curr Infect Dis Rep. VL - 9 UR - https://doi.org/10.1007/s11908-007-0059-3 DO - 10.1007/s11908-007-0059-3 ID - Yende2007 ER - TY - JOUR AU - Karlsson, S. AU - Ruokonen, E. AU - Varpula, T. AU - Ala-Kokko, T. I. AU - Pettilä, V. PY - 2009 DA - 2009// TI - Long-term outcome and quality-adjusted life years after severe sepsis JO - Crit Care Med. VL - 37 UR - https://doi.org/10.1097/CCM.0b013e31819c13ac DO - 10.1097/CCM.0b013e31819c13ac ID - Karlsson2009 ER - TY - JOUR AU - Weycker, D. AU - Akhras, K. S. AU - Edelsberg, J. AU - Angus, D. C. AU - Oster, G. PY - 2003 DA - 2003// TI - Long-term mortality and medical care charges in patients with severe sepsis JO - Crit Care Med. VL - 31 UR - https://doi.org/10.1097/01.CCM.0000085178.80226.0B DO - 10.1097/01.CCM.0000085178.80226.0B ID - Weycker2003 ER - TY - JOUR AU - Carson, W. F. AU - Cavassani, K. A. AU - Dou, Y. AU - Kunkel, S. L. PY - 2011 DA - 2011// TI - Epigenetic regulation of immune cell functions during post-septic immunosuppression JO - Epigenetics. VL - 6 UR - https://doi.org/10.4161/epi.6.3.14017 DO - 10.4161/epi.6.3.14017 ID - Carson2011 ER - TY - JOUR AU - Markwart, R. AU - Condotta, S. A. AU - Requardt, R. P. AU - Borken, F. AU - Schubert, K. AU - Weigel, C. PY - 2014 DA - 2014// TI - Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function JO - PLoS One. VL - 9 UR - https://doi.org/10.1371/journal.pone.0115094 DO - 10.1371/journal.pone.0115094 ID - Markwart2014 ER - TY - JOUR AU - Condotta, S. A. AU - Khan, S. H. AU - Rai, D. AU - Griffith, T. S. AU - Badovinac, V. P. PY - 2015 DA - 2015// TI - Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion JO - J Immunol. VL - 195 UR - https://doi.org/10.4049/jimmunol.1402473 DO - 10.4049/jimmunol.1402473 ID - Condotta2015 ER - TY - JOUR AU - Weiterer, S. AU - Uhle, F. AU - Lichtenstern, C. AU - Siegler, B. H. AU - Bhuju, S. AU - Jarek, M. PY - 2015 DA - 2015// TI - Sepsis induces specific changes in histone modification patterns in human monocytes JO - PLoS One. VL - 10 UR - https://doi.org/10.1371/journal.pone.0121748 DO - 10.1371/journal.pone.0121748 ID - Weiterer2015 ER - TY - JOUR AU - Anderson, S. T. AU - O’Callaghan, E. K. AU - Commins, S. AU - Coogan, A. N. PY - 2015 DA - 2015// TI - Does prior sepsis alter subsequent circadian and sickness behaviour response to lipopolysaccharide treatment in mice? JO - J Neural Transm VL - 122 UR - https://doi.org/10.1007/s00702-013-1124-8 DO - 10.1007/s00702-013-1124-8 ID - Anderson2015 ER - TY - JOUR AU - Anderson, S. T. AU - Commins, S. AU - Moynagh, P. N. AU - Coogan, A. N. PY - 2015 DA - 2015// TI - Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse JO - Brain Behav Immun. VL - 43 UR - https://doi.org/10.1016/j.bbi.2014.07.007 DO - 10.1016/j.bbi.2014.07.007 ID - Anderson2015 ER - TY - JOUR AU - Benjamim, C. F. AU - Hogaboam, C. M. AU - Lukacs, N. W. AU - Kunkel, S. L. PY - 2003 DA - 2003// TI - Septic mice are susceptible to pulmonary aspergillosis JO - Am J Pathol. VL - 163 UR - https://doi.org/10.1016/S0002-9440(10)63615-2 DO - 10.1016/S0002-9440(10)63615-2 ID - Benjamim2003 ER - TY - JOUR AU - Deng, J. C. PY - 2006 DA - 2006// TI - Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M JO - J Clin Invest. VL - 116 ID - Deng2006 ER - TY - JOUR AU - Davis, C. G. AU - Chang, K. AU - Osborne, D. AU - Walton, A. H. AU - Dunne, W. M. AU - Muenzer, J. T. PY - 2011 DA - 2011// TI - Increased susceptibility to Candida infection following cecal ligation and puncture JO - Biochem Biophys Res Commun. VL - 414 UR - https://doi.org/10.1016/j.bbrc.2011.09.017 DO - 10.1016/j.bbrc.2011.09.017 ID - Davis2011 ER - TY - JOUR AU - Boomer, J. S. AU - Shuherk-Shaffer, J. AU - Hotchkiss, R. S. AU - Green, J. M. PY - 2012 DA - 2012// TI - A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis JO - Crit Care. VL - 16 UR - https://doi.org/10.1186/cc11404 DO - 10.1186/cc11404 ID - Boomer2012 ER - TY - JOUR AU - Zhang, Y. AU - Li, J. AU - Lou, J. AU - Zhou, Y. AU - Bo, L. AU - Zhu, J. PY - 2011 DA - 2011// TI - Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients JO - Crit Care. VL - 15 UR - https://doi.org/10.1186/cc10059 DO - 10.1186/cc10059 ID - Zhang2011 ER - TY - JOUR AU - Chang, K. C. AU - Burnham, C. -. A. AU - Compton, S. M. AU - Rasche, D. P. AU - Mazuski, R. AU - McDonough, J. S. PY - 2013 DA - 2013// TI - Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis JO - Crit Care. VL - 17 UR - https://doi.org/10.1186/cc12711 DO - 10.1186/cc12711 ID - Chang2013 ER - TY - JOUR AU - Monneret, G. AU - Venet, F. AU - Pachot, A. AU - Lepape, A. PY - 2008 DA - 2008// TI - Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony JO - Mol Med. VL - 14 UR - https://doi.org/10.2119/2007-00102.Monneret DO - 10.2119/2007-00102.Monneret ID - Monneret2008 ER - TY - JOUR AU - Monneret, G. AU - Lepape, A. AU - Voirin, N. AU - Bohé, J. AU - Venet, F. AU - Debard, A. -. L. PY - 2006 DA - 2006// TI - Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock JO - Intensive Care Med. VL - 32 UR - https://doi.org/10.1007/s00134-006-0204-8 DO - 10.1007/s00134-006-0204-8 ID - Monneret2006 ER - TY - JOUR AU - Cheron, A. AU - Floccard, B. AU - Allaouchiche, B. AU - Guignant, C. AU - Poitevin, F. AU - Malcus, C. PY - 2010 DA - 2010// TI - Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma JO - Crit Care. VL - 14 UR - https://doi.org/10.1186/cc9331 DO - 10.1186/cc9331 ID - Cheron2010 ER - TY - JOUR AU - Landelle, C. AU - Lepape, A. AU - Voirin, N. AU - Tognet, E. AU - Venet, F. AU - Bohé, J. PY - 2010 DA - 2010// TI - Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock JO - Intensive Care Med. VL - 36 UR - https://doi.org/10.1007/s00134-010-1962-x DO - 10.1007/s00134-010-1962-x ID - Landelle2010 ER - TY - JOUR AU - Lukaszewicz, A. -. C. AU - Grienay, M. AU - Resche-Rigon, M. AU - Pirracchio, R. AU - Faivre, V. AU - Boval, B. PY - 2009 DA - 2009// TI - Monocytic HLA-DR expression in intensive care patients: interest for prognosis and secondary infection prediction JO - Crit Care Med. VL - 37 UR - https://doi.org/10.1097/CCM.0b013e3181ab858a DO - 10.1097/CCM.0b013e3181ab858a ID - Lukaszewicz2009 ER - TY - JOUR AU - Demaret, J. AU - Walencik, A. AU - Jacob, M. -. C. AU - Timsit, J. -. F. AU - Venet, F. AU - Lepape, A. PY - 2013 DA - 2013// TI - Inter-laboratory assessment of flow cytometric monocyte HLA-DR expression in clinical samples JO - Cytometry B Clin Cytom. VL - 84 UR - https://doi.org/10.1002/cyto.b.21043 DO - 10.1002/cyto.b.21043 ID - Demaret2013 ER -