Skip to main content

Advertisement

Table 2 Comparison of AKI progressors and non-progressors

From: Anaemia is not a risk factor for progression of acute kidney injury: a retrospective analysis

Parameters All (n = 210)* Did not progress to AKI III (n = 120) Progressed to AKI III (n = 85) p value
Age, median (IQR) 70.5 (57–77) 70 (54–76) 71 (60–78) 0.13
Male gender, n (%) 138 (67.3) 79 (65.8) 59 (69.4) 0.59
CAD/CCF, n (%) 92 (44) 41 (34.2) 49 (57.7) 0.001
Severity of illness on admission to ICU     
 SOFA score, mean (SD) 7.1 (2.8) 6.9 (2.7) 7.5 (2.9) 0.14
 APACHE II score, median (IQR) 18 (14–22) 17 (13–21) 18 (15–22) 0.09
Parameters on day of AKI I     
 SOFA score, mean (SD) 8.7 (2.7) 8.0 (2.5) 9.6 (2.8) <0.001
 Presence of sepsis, n (%) 125 (60) 79 (66.4) 43 (50.6) 0.02
 DO2I (ml/min/m2), median (IQR) 362 (277–482) 405 (302–514) 325 (266–401) <0.001
 SaO2 0.95 (0.94–0.96) 0.95 (0.94–0.96) 0.95 (0.94–0.96) 0.81
 Hb (g/L), median (IQR) 96 (88–105) 96 (90–105) 96 (85–105) 0.64
 Cardiac index (L/min/m2), median (IQR) 3.0 (2.3–3.9) 3.3 (2.5–4.2) 2.6 (2.1–3.3) <0.001
 Arterial lactate (mmol/L), median (IQR) 1.8 (1.3–2.6) 1.6 (1.1–2.3) 2 (1.5–3) <0.001
 CVP (cmH2O), median (IQR) 14 (10–18) 13 (10–17) 16 (11–19) 0.02
 MAP (mmHg), median (IQR) 73 (69–78) 74 (70–79) 71 (68–77) 0.01
 Vasopressor/inotrope therapy, n (%) 187 (8) 100 (83.3) 82 (96.5) 0.003
 Mechanical ventilation, n (%) 191 (91) 103 (85.8) 84 (98.8) 0.001
 Urine output (mL/h), median (IQR) 61 (38–94) 66 (46–104) 54 (32–79) 0.002
 Cumulative fluid balance (ml), median (IQR) 2361 (952–3812) 2379 (935–4222) 2363 (974–3719) 0.995
Outcome     
 ICU mortality, % 32.4 11.7 57.6 <0.001
 Hospital mortality, % 43.3 24.2 67.1 <0.001
  1. *Including 5 patients who died before their renal function recovered or progressed
  2. AKI acute kidney injury, APACHE Acute Physiology and Chronic Health Evaluation, CAD coronary artery disease, CCF congestive cardiac failure, CVP central venous pressure, DO 2 I systemic oxygen delivery index, ICU intensive care unit, IQR interquartile range, Hb haemoglobin, MAP mean arterial pressure, SaO 2 arterial oxygen saturation, SD standard deviation, SOFA Sequential Organ Failure Assessment