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Table 2 Comparison of AKI progressors and non-progressors

From: Anaemia is not a risk factor for progression of acute kidney injury: a retrospective analysis

Parameters

All (n = 210)*

Did not progress to AKI III (n = 120)

Progressed to AKI III (n = 85)

p value

Age, median (IQR)

70.5 (57–77)

70 (54–76)

71 (60–78)

0.13

Male gender, n (%)

138 (67.3)

79 (65.8)

59 (69.4)

0.59

CAD/CCF, n (%)

92 (44)

41 (34.2)

49 (57.7)

0.001

Severity of illness on admission to ICU

    

 SOFA score, mean (SD)

7.1 (2.8)

6.9 (2.7)

7.5 (2.9)

0.14

 APACHE II score, median (IQR)

18 (14–22)

17 (13–21)

18 (15–22)

0.09

Parameters on day of AKI I

    

 SOFA score, mean (SD)

8.7 (2.7)

8.0 (2.5)

9.6 (2.8)

<0.001

 Presence of sepsis, n (%)

125 (60)

79 (66.4)

43 (50.6)

0.02

 DO2I (ml/min/m2), median (IQR)

362 (277–482)

405 (302–514)

325 (266–401)

<0.001

 SaO2

0.95 (0.94–0.96)

0.95 (0.94–0.96)

0.95 (0.94–0.96)

0.81

 Hb (g/L), median (IQR)

96 (88–105)

96 (90–105)

96 (85–105)

0.64

 Cardiac index (L/min/m2), median (IQR)

3.0 (2.3–3.9)

3.3 (2.5–4.2)

2.6 (2.1–3.3)

<0.001

 Arterial lactate (mmol/L), median (IQR)

1.8 (1.3–2.6)

1.6 (1.1–2.3)

2 (1.5–3)

<0.001

 CVP (cmH2O), median (IQR)

14 (10–18)

13 (10–17)

16 (11–19)

0.02

 MAP (mmHg), median (IQR)

73 (69–78)

74 (70–79)

71 (68–77)

0.01

 Vasopressor/inotrope therapy, n (%)

187 (8)

100 (83.3)

82 (96.5)

0.003

 Mechanical ventilation, n (%)

191 (91)

103 (85.8)

84 (98.8)

0.001

 Urine output (mL/h), median (IQR)

61 (38–94)

66 (46–104)

54 (32–79)

0.002

 Cumulative fluid balance (ml), median (IQR)

2361 (952–3812)

2379 (935–4222)

2363 (974–3719)

0.995

Outcome

    

 ICU mortality, %

32.4

11.7

57.6

<0.001

 Hospital mortality, %

43.3

24.2

67.1

<0.001

  1. *Including 5 patients who died before their renal function recovered or progressed
  2. AKI acute kidney injury, APACHE Acute Physiology and Chronic Health Evaluation, CAD coronary artery disease, CCF congestive cardiac failure, CVP central venous pressure, DO 2 I systemic oxygen delivery index, ICU intensive care unit, IQR interquartile range, Hb haemoglobin, MAP mean arterial pressure, SaO 2 arterial oxygen saturation, SD standard deviation, SOFA Sequential Organ Failure Assessment