Corticosteroid treatment | ||||
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Characteristics and cointerventions | Univariable analysis, OR (95 % CI) | p Value | Multivariable analysis, OR (95 % CI) | p Value |
Age (per 1-year increase) | 1.01 (1.00, 1.02) | 0.04 | 1.06 (0.99, 1.02) | 0.41 |
Female sex | 1.18 (0.86, 1.63) | 0.31 | 1.33 (0.92, 1.92) | 0.13 |
APACHE II score (per 1-point increase) | 1.01 (0.99, 1.03) | 0.21 | 1.01 (0.99, 1.03) | 0.37 |
Number of comorbidities per patient (per 1 increase) | 1.17 (1.09, 1.26) | <0.001 | 1.04 (0.93, 1.15) | 0.51 |
Pulmonary comorbidity | 3.24 (2.27, 4.63) | <0.001 | 3.82 (2.48, 5.87) | <0.001 |
Cardiac disease | 1.51 (0.96, 2.38) | 0.07 | 1.00 (0.55, 1.81) | 0.99 |
Immune suppressiona | 3.09 (1.46, 6.54) | 0.003 | 3.58 (1.59, 8.06) | 0.002 |
Septic shock at admissionb | 1.52 (0.93, 2.48) | 0.09 | 2.20 (1.25, 3.88) | 0.006 |
Bacterial coinfection at admission | 0.80 (0.57, 1.13) | 0.19 | 0.71 (0.48, 1.05) | 0.09 |