Variable | Bacteremia patients (n = 1,060) | Fungemia patients (n = 96) | P value |
---|---|---|---|
Delay between ICU admission and BSI, days, median (IQR) | 8 (3–16) | 9 (3–15.5) | 0.9812 |
Delay between hospital admission and BSI, days, median (IQR) | 13 (7–25) | 20 (10.5–30.5) | 0.1299 |
Delay to positivity of the blood culture sampling, days, median (IQR) | 38.1 (21.1–69.2) | 48.7 (33–81) | 0.0004 |
Sepsis syndrome | 0.5420 | ||
Sepsis, n (%) | 136 (12.8) | 14 (14.6) | |
Severe sepsis, n (%) | 442 (41.7) | 34 (35.4) | |
Septic shock, n (%) | 482 (45.5) | 48 (50) | |
SOFA score | 0.4812 | ||
0–4, n (%) | 256 (24.2) | 17 (17.7) | |
5–7, n (%) | 284 (26.8) | 24 (25) | |
8–11, n (%) | 300 (28.3) | 31 (32.3) | |
≥12, n (%) | 220 (20.8) | 24 (25) | |
SOFA respiratory ≥3, n (%) | 499 (47.1) | 45 (46.9) | 0.9385 |
SOFA cardiovascular ≥3, n (%) | 441 (41.6) | 47 (49) | 0.2493 |
SOFA neurological ≥3, n (%) | 340 (32.1) | 32 (33.3) | 0.6578 |
SOFA renal ≥3, n (%) | 172 (16.2) | 25 (26) | 0.0273 |
SOFA coagulation ≥3, n (%) | 134 (12.6) | 15 (15.6) | 0.5577 |
SOFA liver ≥3, n (%) | 81 (7.6) | 7 (7.3) | 0.7845 |
Need for mechanical ventilation, n (%) | 946 (89.2) | 84 (87.5) | 0.6661 |
Hypotension, n (%) | 529 (49.9) | 54 (56.3) | 0.3263 |
Presumed source of infection | 0.3336 | ||
No clear source, n (%) | 242 (22.8) | 32 (33.3) | |
Catheter-related, n (%) | 226 (21.3) | 21 (21.9) | |
Respiratory, n (%) | 230 (21.7) | 14 (14.6) | |
Intra-abdominal, n (%) | 122 (11.5) | 12 (12.5) | |
Urinary, n (%) | 43 (4.1) | 4 (4.2) | |
Others, n (%) | 67 (6.3) | 6 (6.3) | |
Multiple sources, n (%) | 130 (12.3) | 7 (7.3) | |
Source control | 0.9820 | ||
Not required, n (%) | 590 (55.7) | 54 (56.3) | |
Done, n (%) | 429 (40.5) | 38 (39.6) | |
Required not done, n (%) | 41 (3.9) | 4 (4.2) | |
Delay of adequate treatment | <0.0001 | ||
<24 h | 586 (55.3) | 22 (22.9) | |
>24 h and ≤120 h | 335 (31.6) | 59 (61.5) | |
>120 h | 40 (3.8) | 9 (9.4) | |
Never | 99 (9.3) | 6 (6.2) |