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Table 2 Characteristics of fungemia and bacteremia episodes at diagnosis

From: Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study

Variable

Bacteremia patients (n = 1,060)

Fungemia patients (n = 96)

P value

Delay between ICU admission and BSI, days, median (IQR)

8 (3–16)

9 (3–15.5)

0.9812

Delay between hospital admission and BSI, days, median (IQR)

13 (7–25)

20 (10.5–30.5)

0.1299

Delay to positivity of the blood culture sampling, days, median (IQR)

38.1 (21.1–69.2)

48.7 (33–81)

0.0004

Sepsis syndrome

  

0.5420

 Sepsis, n (%)

136 (12.8)

14 (14.6)

 

 Severe sepsis, n (%)

442 (41.7)

34 (35.4)

 

 Septic shock, n (%)

482 (45.5)

48 (50)

 

SOFA score

  

0.4812

 0–4, n (%)

256 (24.2)

17 (17.7)

 

 5–7, n (%)

284 (26.8)

24 (25)

 

 8–11, n (%)

300 (28.3)

31 (32.3)

 

 ≥12, n (%)

220 (20.8)

24 (25)

 

SOFA respiratory ≥3, n (%)

499 (47.1)

45 (46.9)

0.9385

SOFA cardiovascular ≥3, n (%)

441 (41.6)

47 (49)

0.2493

SOFA neurological ≥3, n (%)

340 (32.1)

32 (33.3)

0.6578

SOFA renal ≥3, n (%)

172 (16.2)

25 (26)

0.0273

SOFA coagulation ≥3, n (%)

134 (12.6)

15 (15.6)

0.5577

SOFA liver ≥3, n (%)

81 (7.6)

7 (7.3)

0.7845

Need for mechanical ventilation, n (%)

946 (89.2)

84 (87.5)

0.6661

Hypotension, n (%)

529 (49.9)

54 (56.3)

0.3263

Presumed source of infection

  

0.3336

 No clear source, n (%)

242 (22.8)

32 (33.3)

 

 Catheter-related, n (%)

226 (21.3)

21 (21.9)

 

 Respiratory, n (%)

230 (21.7)

14 (14.6)

 

 Intra-abdominal, n (%)

122 (11.5)

12 (12.5)

 

 Urinary, n (%)

43 (4.1)

4 (4.2)

 

 Others, n (%)

67 (6.3)

6 (6.3)

 

 Multiple sources, n (%)

130 (12.3)

7 (7.3)

 

Source control

  

0.9820

 Not required, n (%)

590 (55.7)

54 (56.3)

 

 Done, n (%)

429 (40.5)

38 (39.6)

 

 Required not done, n (%)

41 (3.9)

4 (4.2)

 

Delay of adequate treatment

  

<0.0001

 <24 h

586 (55.3)

22 (22.9)

 

 >24 h and ≤120 h

335 (31.6)

59 (61.5)

 

 >120 h

40 (3.8)

9 (9.4)

 

 Never

99 (9.3)

6 (6.2)

 
  1. SOFA Sequential Organ Failure Assessment