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Table 1 Baseline and clinical characteristics of study patients

From: Daily urinary urea excretion to guide intermittent hemodialysis weaning in critically ill patients

Variables

All patients (n = 67)

Unweaned (n = 30)

Weaned (n = 37)

P value

Age, years

64 (52–73)

63 (47–67)

65 (55–73)

0.22

Male sex, n (%)

48 (71.6)

25 (83.3)

23 (62.1)

0.06

Admission type, n (%)

   

0.09

 Medical

55 (82.1)

27 (90.0)

28 (75.7)

 

 Unscheduled surgery

11 (16.4)

2 (6.6)

9 (24.3)

 

 Scheduled surgery

1 (1.4)

1 (3.3)

0 (0)

 

BMI, kg/m2

26 (23–31)

25 (21–30)

28 (25–31)

0.22

SOFA score, points

9 (6–13)

9 (6–10)

11 (7–14)

0.07

SAPS2 score, points

61 (45–72)

58 (44–68)

64 (46–73)

0.37

McCabe score, n (%)

   

0.54

 0

49 (73.1)

20 (66.7)

29 (78.7)

 

 1

14 (20.9)

8 (26.7)

6 (16.2)

 

 2

4 (5.9)

2 (6.7)

2 (5.4)

 

Baseline GFRa, n (%)

   

<0.001

 >90 ml/min/1.73 m2

13 (19.4)

2 (6.7)

11 (29.7)

 

 60–90 ml/min/1.73 m2

16 (23.9)

4 (13.3)

12 (32.4)

 

 30–60 ml/min/1.73 m2

16 (23.9)

7 (23.3)

9 (24.3)

 

 15–30 ml/min/1.73 m2

16 (23.9)

11 (36.7)

5 (13.5)

 

 <15 ml/min/1.73 m2

6 (9.0)

6 (20.0)

0 (0.0)

 

Contributing factors to AKI, n (%)

    

 Ischemia

60 (89.6)

26 (86.6)

34 (91.8)

0.49

 Nephrotoxicity

18 (26.8)

10 (33.3)

8 (24.3)

0.28

 Sepsis

42 (62.7)

18 (60.0)

24 (64.8)

0.68

 Other

9 (13.4)

4 (13.3)

5 (13.5)

0.98

Length of ICU stay, days

18 (10–31)

11 (7–15)

26 (17–42)

0.01

Renal replacement therapy, days

11 (7–15)

10 (7–15)

11 (8–15)

0.90

Diuretic at the last dialysis session, n (%)

7 (10.4)

1 (3.3)

6 (16.2)

0.09

Mechanical ventilation during ICU stay, n (%)

46 (68.7)

17 (56.7)

29 (78.3)

0.06

Amines during ICU stay, n (%)

47 (70.1)

15 (50.0)

32 (86.5)

0.01

  1. AKI acute kidney injury, BMI body mass index, GFR glomerular filtration rate estimated using Modified Diet in Renal Disease equation, ICU intensive care unit, RRT renal replacement therapy, SAPS2 Simplified Acute Physiological Score II, SOFA sequential organ failure assessment
  2. Data are presented as median (interquartile range) or count (%)
  3. aBaseline GFR classified according to Kidney Disease: Improving Global Outcomes classification