From: Daily urinary urea excretion to guide intermittent hemodialysis weaning in critically ill patients
Variables | All patients (n = 67) | Unweaned (n = 30) | Weaned (n = 37) | P value |
---|---|---|---|---|
Age, years | 64 (52–73) | 63 (47–67) | 65 (55–73) | 0.22 |
Male sex, n (%) | 48 (71.6) | 25 (83.3) | 23 (62.1) | 0.06 |
Admission type, n (%) | 0.09 | |||
Medical | 55 (82.1) | 27 (90.0) | 28 (75.7) | |
Unscheduled surgery | 11 (16.4) | 2 (6.6) | 9 (24.3) | |
Scheduled surgery | 1 (1.4) | 1 (3.3) | 0 (0) | |
BMI, kg/m2 | 26 (23–31) | 25 (21–30) | 28 (25–31) | 0.22 |
SOFA score, points | 9 (6–13) | 9 (6–10) | 11 (7–14) | 0.07 |
SAPS2 score, points | 61 (45–72) | 58 (44–68) | 64 (46–73) | 0.37 |
McCabe score, n (%) | 0.54 | |||
0 | 49 (73.1) | 20 (66.7) | 29 (78.7) | |
1 | 14 (20.9) | 8 (26.7) | 6 (16.2) | |
2 | 4 (5.9) | 2 (6.7) | 2 (5.4) | |
Baseline GFRa, n (%) | <0.001 | |||
>90 ml/min/1.73 m2 | 13 (19.4) | 2 (6.7) | 11 (29.7) | |
60–90 ml/min/1.73 m2 | 16 (23.9) | 4 (13.3) | 12 (32.4) | |
30–60 ml/min/1.73 m2 | 16 (23.9) | 7 (23.3) | 9 (24.3) | |
15–30 ml/min/1.73 m2 | 16 (23.9) | 11 (36.7) | 5 (13.5) | |
<15 ml/min/1.73 m2 | 6 (9.0) | 6 (20.0) | 0 (0.0) | |
Contributing factors to AKI, n (%) | ||||
Ischemia | 60 (89.6) | 26 (86.6) | 34 (91.8) | 0.49 |
Nephrotoxicity | 18 (26.8) | 10 (33.3) | 8 (24.3) | 0.28 |
Sepsis | 42 (62.7) | 18 (60.0) | 24 (64.8) | 0.68 |
Other | 9 (13.4) | 4 (13.3) | 5 (13.5) | 0.98 |
Length of ICU stay, days | 18 (10–31) | 11 (7–15) | 26 (17–42) | 0.01 |
Renal replacement therapy, days | 11 (7–15) | 10 (7–15) | 11 (8–15) | 0.90 |
Diuretic at the last dialysis session, n (%) | 7 (10.4) | 1 (3.3) | 6 (16.2) | 0.09 |
Mechanical ventilation during ICU stay, n (%) | 46 (68.7) | 17 (56.7) | 29 (78.3) | 0.06 |
Amines during ICU stay, n (%) | 47 (70.1) | 15 (50.0) | 32 (86.5) | 0.01 |