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low risk, high risk, unclear risk, p plasma, u urine
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1 unknown whether a consecutive or random sample of patients enrolled, 2 unknown whether the index test results interpreted without knowledge of the results of the reference standard or unknown whether the threshold was prespecified, 3 unclear whether the reference standard results were interpreted without knowledge of the results of the index test, 4 unknown whether all patients were included in the analysis, # unknown whether enrolling a consecutive or random sample without introduction
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QUADAS-2 Quality Assessment of Diagnostic Accuracy Studies 2