|
Time (h)
|
8.00
|
8.00
|
8.00
|
20.00
|
8.00
|
20.00
|
|
Patients (number)
|
15
|
15
|
10
|
10
|
8
|
6
|
|
VT (mL/kg)
|
6.2 ± 0.7
|
4.29 ± 0.5*
|
4.58 ± 0.7*
|
4.59 ± 0.8*
|
4.8 ± 0.7*
|
4.8 ± 0.7*
|
|
Respiratory rate (beats/minute)
|
28 ± 7
|
31.6 ± 4.6*
|
29.6 ± 6.8
|
29.6 ± 6.8
|
28 ± 7
|
27.4 ± 8.6
|
|
Positive end-expiratory pressure (cmH2O)
|
12 ± 3
|
14 ± 2
|
13 ± 3
|
12 ± 4
|
13 ± 5
|
13 ± 3
|
|
Arterial partial pressure of oxygen/inspired oxygen fraction
|
159 ± 34
|
175 ± 45
|
185 ± 91
|
190 57
|
176 ± 59
|
176 ± 80
|
|
Plateau pressure (cmH2O)
|
27.7 ± 1.6
|
23.9 ± 1*
|
24 ± 4*
|
24 ± 3*
|
24 ± 3*
|
23 ± 3*
|
|
Blood flow (ml/min)
| |
435 ± 60
|
424 ± 63
|
423 ± 35
|
424 ± 29
|
436 ± 39
|
|
Rotations per minute (RPM)
| |
1407 ± 26
|
1408 ± 30
|
1409 ± 32
|
1411 ± 36
|
1414 ± 41
|
|
Sweep gas (L/min)
| |
8.6 ± 3.5
|
9.2 ± 2.9
|
9 ± 3
|
9.9 ± 0.3
|
8.7 ± 3.2
|
|
CO2 removal (ml/min)
| |
81 ± 9
|
70 ± 29
|
70 ± 31
|
81 ± 22
|
71 ± 11
|
|
Ph
|
7.36 ± 0.1
|
7.33 ± 0.1
|
7.39 ± 0.1
|
7.36 ± 0.1
|
7.33 ± 0.1
|
7.4 ± 0.1
|
|
PaO2 (mmHg)
|
95 ± 29
|
90 ± 22
|
91 ± 26
|
84 ± 10
|
81 ± 15
|
99 ± 29
|
|
PaCO2 (mmHg)
|
51 ± 15
|
53 ± 15
|
51 ± 18
|
52 ± 17
|
55 ± 20
|
49 ± 11
|
|
HCO3 (mmol/L)
|
28 ± 5
|
27.6 ± 6.1
|
28.7 ± 6.2
|
28. ± 6.9
|
28.1 ± 7.4
|
28.3 ± 6.03
|
|
Lactate (mmol/L)
|
2 ± 1
|
2.9 ± 4.8
|
1.9 ± 1.7
|
1.8 ± 1.8
|
1.9 ± 2.0
|
1.3 ± 0.4
|
|
Heart rate (beats/minute)
|
76 ± 9
|
90 ± 17
|
86 ± 15
|
95 ± 21
|
94 ± 19
|
94 ± 17
|
|
Mean arterial pressure (mmHg)
|
98 ± 20
|
74 ± 14
|
80 ± 10
|
76 ± 12
|
76 ± 19
|
85 ± 14
|
|
Norepinephrine dose (mcg/kg/min)
|
0.51 ± 0.6
|
0.45 ± 0.4
|
0.34 ± 0.3
|
0.29 ± 0.27
|
0.57 ± 0.4
|
0.5 ± 0.6
|
