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Table 2 Time course of ventilation variables during the run-in phase

From: Feasibility and safety of low-flow extracorporeal carbon dioxide removal to facilitate ultra-protective ventilation in patients with moderate acute respiratory distress syndrome

Variables

Baseline

VT 5 mL/kg

VT 4.5 mL/kg

VT 4 mL/kg

VT (mL/kg)

6.2 ± 0.7

5.02 ± 0.1*

4.48 ± 0.1*

3.96 ± 0.1*

Respiratory rate (beats/minute)

28 ± 7

29 ± 4

30 ± 4*

30 ± 5*

Positive end-expiratory pressure (cmH2O)

12 ± 3

13.8 ± 3

13.6 ± 4

13.0 ± 4.0

Plateau pressure (cmH2O)

27.7 ± 1.6

25.2 ± 1.6*

23.6 ± 1.3*

22.7 ± 1.8*

Patients who reached the pH threshold for ECCO2R, n

 

0

2

15

  1. *P <0.05 vs baseline. V T tidal volume, ECCO 2 R extracorporeal carbon dioxide removal