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Table 2 Time course of ventilation variables during the run-in phase

From: Feasibility and safety of low-flow extracorporeal carbon dioxide removal to facilitate ultra-protective ventilation in patients with moderate acute respiratory distress syndrome

Variables Baseline VT 5 mL/kg VT 4.5 mL/kg VT 4 mL/kg
VT (mL/kg) 6.2 ± 0.7 5.02 ± 0.1* 4.48 ± 0.1* 3.96 ± 0.1*
Respiratory rate (beats/minute) 28 ± 7 29 ± 4 30 ± 4* 30 ± 5*
Positive end-expiratory pressure (cmH2O) 12 ± 3 13.8 ± 3 13.6 ± 4 13.0 ± 4.0
Plateau pressure (cmH2O) 27.7 ± 1.6 25.2 ± 1.6* 23.6 ± 1.3* 22.7 ± 1.8*
Patients who reached the pH threshold for ECCO2R, n   0 2 15
  1. *P <0.05 vs baseline. V T tidal volume, ECCO 2 R extracorporeal carbon dioxide removal