Veno–veno–arterial extracorporeal membrane oxygenation treatment in patients with severe acute respiratory distress syndrome and septic shock

Table 2 Hemodynamic changes during VVA ECMO support

	Baseline	6 h	12 h	24 h	72 h
LVEF (%)	42.5 [23.5–50.0]			50.0 [40.0–50.0]	50.0 [40.0–55.0]
MAP (mmHg)	40.0	76.0	74.0	85.5	83.0
MAP (mmHg)	[33.0–46.0]	[62.8–101.3]	[71.0–101.0]	[75.3–88.3]	[67.3–94.3]
Norepinephrine^a	0.7 [0.6–0.8]	0.5 [0.2–0.6]	0.3 [0–0.6]	0.1 [0–0.1]	0 [0–0]
Epinephrine^a	0.1 [0.0–0.2]	0 [0–0.1]	0 [0–0]	0 [0–0]	0 [0–0]
Arterial gas profile
PaO₂/FiO₂	57.0	102.3	133.0	147.0	162.5
PaO₂/FiO₂	[51.3–76.2]	[80.3–190.0]	[102.0–413.0]	[111.8–184.0]	[137.3–227.5]
Lactate (mmol/L)	7.8 [6.3–16.3]	5.5 [2.5–14.8]	6.3 [2.0–15.5]	7.0 [3.0–14.0]	5.0 [2.0–5.0]
pH	7.2 [7.1–7.2]	7.4 [7.3–7.5]	7.4 [7.3–7.4]	7.4 [7.4–7.5]	7.5 [7.4–7.5]

The data are presented as median [interquartile range]
VVA veno-venoarterial, ECMO extracorporeal membrane oxygenation, LVEF left ventricle ejection fraction, MAP mean arterial pressure
^aThe dose is in μcg/kg/min

ISSN: 1364-8535