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Fig. 12 | Critical Care

Fig. 12

From: Sepsis 2016 Agra, India

Fig. 12

(abstract P4). Contribution of phenolic acids and cytokines to the mitochondrial dysfunction. Cytokines indirectly (through signaling molecules) inhibit pyruvate dehydrogenase and induce NO and ROS production. Some of bacterial phenolic acid directly inhibit NAD-dependent oxidation and regulate ROS production

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