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Table 2 Validity values of skin and needleless connector cultures for prediction of catheter colonization and catheter-related bloodstream infection

From: Assessment of central venous catheter colonization using surveillance culture of withdrawn connectors and insertion site skin

Cultures

S %

SP %

PPV %

NPV %

Validity index

Prevalence

LR+

LR

(95 % CI)

(95 % CI)

(95 % CI)

(95 % CI)

(95 % CI)

(95 % CI)

(95 % CI)

(95 % CI)

Catheter colonization

Skin + NCs

80.0

55.2

28.6

92.5

59.8

18.3

1.79

0.36

(56.4–100)

(42.6–67.9)

(13.7–4434)-

(83.0–100)

(48.5–71.0)

(9.3–27.3)

(1.24–2.58)

(0.13–1.02)

Skin

66.7

82.0

45.4

91.7

79.3

18.3

3.72

0.41

(39.5–93.9)

(72.2–92.0)

(22.4–68.5)

(83.8–99.5)

(69.9–88.6)

(9.3–27.3)

(1.99–6.96)

(0.20–0.84)

NCs

40.0

67.2

21.4

83.3

62.2

18.3

1.22

0.89

(11.9–68.1)

(55.2–79.2)

(4.24–38.4)

(72.5–94.2)

(51.0–73.3)

(9.3–27.3)

(0.60–2.47)

(0.57–1.40)

C-RBSI

Skin + NCs

100

50.6

7.1

100

52.4

3.7

2.03

NA

(83.3–100)

(39.0–62.3)

(0.0–16.1)

(98.7–100)

(41.0–63.9)

(0.0–8.3)

(1.62–2.53)

 

Skin

100

75.9

13.6

100

76.8

3.7

4.16

NA

(83.3–100)

(65.9–86.0)

(0.0–30.2)

(99.2–100)

(67.0–86.6)

(0.0–8.3)

(2.81–6.15)

 

NCs

66.7

67.0

7.1

98.1

67.0

3.7

2.03

0.50

(0.0–100)

(56.0–78.0)

(0.0–18.5)

(93.6–100)

(56.3–77.8)

(0.0–8.3)

(0.86–4.79)

(0.10–2.48)

  1. S sensitivity, SP specificity, PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR− negative likelihood ratio, CI confidence interval, NA not applicable, NC needleless connector, C-RBSI catheter-related bloodstream infection