Table 1 Baseline characteristics of patients with Candida bloodstream infections and critically ill control patients
From: T cells from patients with Candida sepsis display a suppressive immunophenotype
CBSI N = 27 (%) | Critically ill, non-septic patients N = 16 (%) | p value | |||
|---|---|---|---|---|---|
Mean age (±SD), years | 56.9 (23.4) | 58.9 (18.1) | 0.19 | ||
Male gender (%) | 14 (51.9) | 10 (62.5) | 0.46 | ||
APACHE II score (±SD)* | 11.61 (6.7) | 8.69 (4.0) | 0.11 | ||
SOFA score (±SD)* | 4.7 (4.2) | 2.6 (1.8) | 0.06 | ||
White blood cell count (±SD), thousand/mm3 | 11.7 (5.8) | 9.9 (3.5) | 0.25 | ||
Absolute lymphocyte count (±SD), thousand/mm3 | 1.13 (0.99) | 0.61 (0.49) | 0.02 | ||
Absolute neutrophil count (±SD), thousand/mm3 | 7.23 (5.76) | 6.43 (5.32) | 0.77 | ||
Heart rate (±SD), beats/min | 102.2 (19.9) | 109.5 (17.0) | 0.23 | ||
Respiratory rate (±SD), breaths/min | 23.19 (5.6) | 24.4 (4.1) | 0.46 | ||
Baseline creatinine (±SD), mg/dl | 1.46 (1.62) | 1.1 (0.85) | 0.4 | ||
90-day mortality (%) | 6 (22.2) | 3 (18.8) | 0.79 | ||
Primary diagnosis, n (%) | 13 (48) | Candida albicans | 6 (37) | Motor vehicle accident | n/a |
7 (26) | Candida glabrata | 3 (18) | Fall | ||
3 (11) | Candida tropicalis | 2 (13) | Spinal fusion | ||
3 (11) | Candida parapsilosis | 2 (13) | Coronary artery bypass graft | ||
1 (4) | Candida dubliniensis | 2 (13) | Hemorrhage | ||
1 (6) | Spinal cord injury | ||||