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Table 2 Breathing pattern and EAdi parameters during the SBTs and gas exchange parameters immediately before each SBT

From: Impact of prolonged assisted ventilation on diaphragmatic efficiency: NAVA versus PSV

 

PSV group

NAVA group

 

0 h

24 h

48 h

0 h

24 h

48 h

CPAP (cmH2O)

8.43 ± 2.4

8.02 ± 2.8

8.09 ± 1.54

8.3 ± 2.3

8 ± 2.7

7.8 ± 2.8

VT (ml)

404 ± 185

413 ± 154

412 ± 172

378 ± 124

375 ± 120

408 ± 120

RR (breaths/minute)

25.9 ± 12.2

23.7 ± 9.1

23.7 ± 6.7

24.3 ± 6.5

24 ± 7.8

23.6 ± 8.4

Ti,NEUR (s)

0.94 ± 0.36

0.93 ± 0.33

0.93 ± 0.26

0.87 ± 0.25

0.80 ± 0.18

0.82 ± 0.39

Flow peak (L/s)

0.60 ± 0.2

0.59 ± 0.1

0.55 ± 0.11

0.66 ± 0.27

0.68 ± 0.3

0.66 ± 0.2

EAdiPEAK (μV)

14.2 ± 6.2

17.2 ± 6.7*

19.06 ± 9.2*

18.9 ± 10.1

13.2 ± 8.9*

9.2 ± 5.5*§

pH

7.41 ± 0.1

7.41 ± 0.1

7.44 ± 0.1

7.46 ± 0.1

7.46 ± 0.1

7.45 ± 0.1

PaO2/FiO2

214 ± 70

231 ± 86

231 ± 93

239 ± 75

260 ± 75

289 ± 72

PaCO2 (mmHg)

46.3 ± 12.4

46 ± 11.5

45.6 ± 9.9

45.5 ± 11.4

46.4 ± 11.1

47.6 ± 14.6

HCO3 (mEq/L)

29.43 ± 6.2

29.7 ± 6.3

30.6 ± 7.2

31.5 ± 5.5

33 ± 5.6

32.6 ± 7.9

RASS score

–0.5 ± 1

–0.33 ± 1.15

–0.25 ± 1.14

–0.38 ± 1.04

–0.46 ± 1.13

– 0.54 ± 1.05

  1. *p <0,006 versus 0 h, same group; § p <0,006 between groups, same time point. EAdi diaphragm electrical acivity, SBT spontaneous breathing trial, NAVA neurally adjusted ventilator assist, PSV pressure support ventilation, CPAP continuous positive airway pressure VT tidal volume, RR respiratory rate, Ti, NEUR neural inspiratory time, PaO 2 arterial oxygen partial pressure, FiO 2 inspiratory oxygen fraction, PaCO 2 arterial carbon dioxyde partial pressure, RASS Richmond agitation sedation scale [23]